Genetic loci associated with heart rate variability and their effects on cardiac disease risk
Identifieur interne : 000B74 ( Main/Exploration ); précédent : 000B73; suivant : 000B75Genetic loci associated with heart rate variability and their effects on cardiac disease risk
Auteurs : Ilja M. Nolte [Pays-Bas] ; M. Loretto Munoz [Pays-Bas] ; Vinicius Tragante [Pays-Bas] ; Azmeraw T. Amare [Pays-Bas, Australie, Éthiopie] ; Rick Jansen [Pays-Bas] ; Ahmad Vaez [Pays-Bas, Iran] ; Benedikt Von Der Heyde [Suède] ; Christy L. Avery [États-Unis] ; Joshua C. Bis [États-Unis] ; Bram Dierckx [Pays-Bas] ; Jenny Van Dongen [Pays-Bas] ; Stephanie M. Gogarten [États-Unis] ; Philippe Goyette [Canada] ; Jussi Hernesniemi [Finlande] ; Ville Huikari [Finlande] ; Shih-Jen Hwang [États-Unis] ; Deepali Jaju ; Kathleen F. Kerr [États-Unis] ; Alexander Kluttig [Allemagne] ; Bouwe P. Krijthe [Pays-Bas] ; Jitender Kumar [Suède] ; Sander W. Van Der Laan [Pays-Bas] ; Leo-Pekka Lyytik Inen [Finlande] ; Adam X. Maihofer [États-Unis] ; Arpi Minassian [États-Unis] ; Peter J. Van Der Most [Pays-Bas] ; Martina Müller-Nurasyid [Allemagne] ; Michel Nivard [Pays-Bas] ; Erika Salvi [Italie] ; James D. Stewart [États-Unis] ; Julian F. Thayer [États-Unis] ; Niek Verweij [Pays-Bas] ; Andrew Wong [Royaume-Uni] ; Delilah Zabaneh [Royaume-Uni] ; Mohammad H. Zafarmand [Pays-Bas] ; Abdel Abdellaoui [Pays-Bas] ; Sulayma Albarwani ; Christine Albert [États-Unis] ; Alvaro Alonso [États-Unis] ; Foram Ashar [États-Unis] ; Juha Auvinen [Finlande] ; Tomas Axelsson [Suède] ; Dewleen G. Baker [États-Unis] ; Paul I. W. De Bakker [Pays-Bas] ; Matteo Barcella [Italie] ; Riad Bayoumi [Émirats arabes unis] ; Rob J. Bieringa [Pays-Bas] ; Dorret Boomsma [Pays-Bas] ; Gabrielle Boucher [Canada] ; Annie R. Britton [Royaume-Uni] ; Ingrid Christophersen [États-Unis, Norvège] ; Andrea Dietrich [Pays-Bas] ; George B. Ehret [États-Unis, Suisse] ; Patrick T. Ellinor [États-Unis] ; Markku Eskola [Finlande] ; Janine F. Felix [Pays-Bas] ; John S. Floras [Canada] ; Oscar H. Franco [Pays-Bas] ; Peter Friberg [Suède] ; Maaike G. J. Gademan [Pays-Bas] ; Mark A. Geyer [États-Unis] ; Vilmantas Giedraitis [Suède] ; Catharina A. Hartman [Pays-Bas] ; Daiane Hemerich [Pays-Bas, Brésil] ; Albert Hofman [Pays-Bas] ; Jouke-Jan Hottenga [Pays-Bas] ; Heikki Huikuri [Finlande] ; Nina Hutri-K Hönen [Finlande] ; Xavier Jouven [France] ; Juhani Junttila [Finlande] ; Markus Juonala [Finlande] ; Antti M. Kiviniemi [Finlande] ; Jan A. Kors [Pays-Bas] ; Meena Kumari [Royaume-Uni] ; Tatiana Kuznetsova [Belgique] ; Cathy C. Laurie [États-Unis] ; Joop D. Lefrandt [Pays-Bas] ; Yong Li [Allemagne] ; Yun Li [États-Unis] ; Duanping Liao [États-Unis] ; Marian C. Limacher [États-Unis] ; Henry J. Lin [États-Unis] ; Cecilia M. Lindgren [Royaume-Uni] ; Steven A. Lubitz [États-Unis] ; Anubha Mahajan [Royaume-Uni] ; Barbara Mcknight [États-Unis] ; Henriette Meyer Zu Schwabedissen [Suisse] ; Yuri Milaneschi [Pays-Bas] ; Nina Mononen [Finlande] ; Andrew P. Morris [Royaume-Uni] ; Mike A. Nalls [États-Unis] ; Gerjan Navis [Pays-Bas] ; Melanie Neijts [Pays-Bas] ; Kjell Nikus [Finlande] ; Kari E. North [États-Unis] ; Daniel T. O'Connor [États-Unis] ; Johan Ormel [Pays-Bas] ; Siegfried Perz [Allemagne] ; Annette Peters [Allemagne] ; Bruce M. Psaty [États-Unis] ; Olli T. Raitakari [Finlande] ; Victoria B. Risbrough [États-Unis] ; Moritz F. Sinner [Allemagne] ; David Siscovick [États-Unis] ; Johannes H. Smit [Pays-Bas] ; Nicholas L. Smith [États-Unis] ; Elsayed Z. Soliman [États-Unis] ; Nona Sotoodehnia [États-Unis] ; Jan A. Staessen [Belgique] ; Phyllis K. Stein [États-Unis] ; Adrienne M. Stilp [États-Unis] ; Katarzyna Stolarz-Skrzypek [Pologne] ; Konstantin Strauch [Allemagne] ; Johan Sundström [Suède] ; Cees A. Swenne [Pays-Bas] ; Ann-Christine Syv Nen [Suède] ; Jean-Claude Tardif [Canada] ; Kent D. Taylor [États-Unis] ; Alexander Teumer [Allemagne] ; Timothy A. Thornton [États-Unis] ; Lesley E. Tinker [États-Unis] ; André G. Uitterlinden [Pays-Bas] ; Jessica Van Setten [Pays-Bas] ; Andreas Voss [Allemagne] ; Melanie Waldenberger [Allemagne] ; Kirk C. Wilhelmsen [États-Unis] ; Gonneke Willemsen [Pays-Bas] ; Quenna Wong [États-Unis] ; Zhu-Ming Zhang [États-Unis] ; Alan B. Zonderman [États-Unis] ; Daniele Cusi [Italie] ; Michele K. Evans [États-Unis] ; Halina K. Greiser [Allemagne] ; Pim Van Der Harst [Pays-Bas] ; Mohammad Hassan ; Erik Ingelsson [Suède, États-Unis] ; Marjo-Riitta J Rvelin [Finlande, Royaume-Uni] ; Stefan K B [Allemagne] ; Mika K Hönen [Finlande] ; Mika Kivimaki [Royaume-Uni] ; Charles Kooperberg [États-Unis] ; Diana Kuh [Royaume-Uni] ; Terho Lehtim Ki [Finlande] ; Lars Lind [Suède] ; Caroline M. Nievergelt [États-Unis] ; Chris J. O'Donnell [États-Unis] ; Albertine J. Oldehinkel [Pays-Bas] ; Brenda Penninx [Pays-Bas] ; Alexander P. Reiner [États-Unis] ; Harriëtte Riese [Pays-Bas] ; Arie M. Van Roon [Pays-Bas] ; John D. Rioux [Canada] ; Jerome I. Rotter [États-Unis] ; Tamar Sofer [États-Unis] ; Bruno H. Stricker [Pays-Bas] ; Henning Tiemeier [Pays-Bas] ; Tanja G. M. Vrijkotte [Pays-Bas] ; Folkert W. Asselbergs [Pays-Bas, Royaume-Uni] ; Bianca J. J. M. Brundel [Pays-Bas] ; Susan R. Heckbert [États-Unis] ; Eric A. Whitsel [États-Unis] ; Marcel Den Hoed [Suède] ; Harold Snieder [Pays-Bas] ; Eco J. C. De Geus [Pays-Bas]Source :
- Nature Communications [ 2041-1723 ] ; 2017.
Abstract
Reduced cardiac vagal control reflected in low heart rate variability (HRV) is associated with greater risks for cardiac morbidity and mortality. In two-stage meta-analyses of genome-wide association studies for three HRV traits in up to 53,174 individuals of European ancestry, we detect 17 genome-wide significant SNPs in eight loci. HRV SNPs tag non-synonymous SNPs (in
Url:
DOI: 10.1038/ncomms15805
PubMed: 28613276
PubMed Central: 5474732
Affiliations:
- Allemagne, Australie, Belgique, Brésil, Canada, Finlande, France, Iran, Italie, Norvège, Pays-Bas, Pologne, Royaume-Uni, Suisse, Suède, Émirats arabes unis, États-Unis, Éthiopie
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Avery</name><affiliation wicri:level="1"><nlm:aff id="a9"><institution>Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bis, Joshua C" sort="Bis, Joshua C" uniqKey="Bis J" first="Joshua C." last="Bis">Joshua C. Bis</name><affiliation wicri:level="1"><nlm:aff id="a10"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>, Seattle, Washington 98104,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Dierckx, Bram" sort="Dierckx, Bram" uniqKey="Dierckx B" first="Bram" last="Dierckx">Bram Dierckx</name><affiliation wicri:level="1"><nlm:aff id="a11"><institution>Department of Child and Adolescent Psychiatry/Psychology, Department of Child and Adolescent Psychiatry</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a12"><institution>The Generation R Study Group, Erasmus MC</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Van Dongen, Jenny" sort="Van Dongen, Jenny" uniqKey="Van Dongen J" first="Jenny" last="Van Dongen">Jenny Van Dongen</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gogarten, Stephanie M" sort="Gogarten, Stephanie M" uniqKey="Gogarten S" first="Stephanie M." last="Gogarten">Stephanie M. Gogarten</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Goyette, Philippe" sort="Goyette, Philippe" uniqKey="Goyette P" first="Philippe" last="Goyette">Philippe Goyette</name><affiliation wicri:level="1"><nlm:aff id="a15"><institution>Montreal Heart Institute</institution>, Montreal, Quebec,<country>Canada</country> H1T 1C8</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hernesniemi, Jussi" sort="Hernesniemi, Jussi" uniqKey="Hernesniemi J" first="Jussi" last="Hernesniemi">Jussi Hernesniemi</name><affiliation wicri:level="1"><nlm:aff id="a16"><institution>Department of Clinical Chemistry, Fimlab Laboratories</institution>, Tampere 33520,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a17"><institution>Department of Clinical Chemistry, University of Tampere School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a18"><institution>Department of Cardiology, Heart Hospital, Tampere University Hospital</institution>, Tampere 33521,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Huikari, Ville" sort="Huikari, Ville" uniqKey="Huikari V" first="Ville" last="Huikari">Ville Huikari</name><affiliation wicri:level="1"><nlm:aff id="a19"><institution>Center for Life Course Health Research, University of Oulu</institution>, Oulu 90014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hwang, Shih Jen" sort="Hwang, Shih Jen" uniqKey="Hwang S" first="Shih-Jen" last="Hwang">Shih-Jen Hwang</name><affiliation wicri:level="1"><nlm:aff id="a20"><institution>Framingham Heart Study</institution>, Framingham, Massachusetts 01702,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a21"><institution>Population Sciences Branch, National Heart, Lung and Blood Institute</institution>, Bethesda, Maryland 20892,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Jaju, Deepali" sort="Jaju, Deepali" uniqKey="Jaju D" first="Deepali" last="Jaju">Deepali Jaju</name><affiliation><nlm:aff id="a22"><institution>Department of Clinical Physiology, Sultan Qaboos University Hospital</institution>, Muscat—Al Khoudh 123,<country>Sultanate of Oman</country></nlm:aff><wicri:noCountry code="nlm country">Sultanate of Oman</wicri:noCountry></affiliation></author><author><name sortKey="Kerr, Kathleen F" sort="Kerr, Kathleen F" uniqKey="Kerr K" first="Kathleen F." last="Kerr">Kathleen F. Kerr</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kluttig, Alexander" sort="Kluttig, Alexander" uniqKey="Kluttig A" first="Alexander" last="Kluttig">Alexander Kluttig</name><affiliation wicri:level="1"><nlm:aff id="a23"><institution>Institute of Medical Epidemiology, Biostatistics and Informatics, Martin-Luther-University Halle-Wittenberg</institution>, Halle (Saale) 06097,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Krijthe, Bouwe P" sort="Krijthe, Bouwe P" uniqKey="Krijthe B" first="Bouwe P." last="Krijthe">Bouwe P. Krijthe</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kumar, Jitender" sort="Kumar, Jitender" uniqKey="Kumar J" first="Jitender" last="Kumar">Jitender Kumar</name><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Department of Medical Sciences, Molecular Epidemiology, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a8"><institution>Science for Life Laboratory, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Laan, Sander W" sort="Van Der Laan, Sander W" uniqKey="Van Der Laan S" first="Sander W." last="Van Der Laan">Sander W. Van Der Laan</name><affiliation wicri:level="1"><nlm:aff id="a25"><institution>Laboratory of Experimental Cardiology, Department of Heart and Lung, University Medical Center Utrecht</institution>, Heidelberglaan 100, Utrecht 3584 CX,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lyytik Inen, Leo Pekka" sort="Lyytik Inen, Leo Pekka" uniqKey="Lyytik Inen L" first="Leo-Pekka" last="Lyytik Inen">Leo-Pekka Lyytik Inen</name><affiliation wicri:level="1"><nlm:aff id="a16"><institution>Department of Clinical Chemistry, Fimlab Laboratories</institution>, Tampere 33520,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a17"><institution>Department of Clinical Chemistry, University of Tampere School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Maihofer, Adam X" sort="Maihofer, Adam X" uniqKey="Maihofer A" first="Adam X." last="Maihofer">Adam X. Maihofer</name><affiliation wicri:level="1"><nlm:aff id="a26"><institution>Department of Psychiatry, University of California, San Diego</institution>, San Diego, California 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a27"><institution>Center for Stress and Mental Health (CESAMH), VA San Diego Healthcare System</institution>, San Diego, California 92161,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Minassian, Arpi" sort="Minassian, Arpi" uniqKey="Minassian A" first="Arpi" last="Minassian">Arpi Minassian</name><affiliation wicri:level="1"><nlm:aff id="a26"><institution>Department of Psychiatry, University of California, San Diego</institution>, San Diego, California 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a27"><institution>Center for Stress and Mental Health (CESAMH), VA San Diego Healthcare System</institution>, San Diego, California 92161,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Most, Peter J" sort="Van Der Most, Peter J" uniqKey="Van Der Most P" first="Peter J." last="Van Der Most">Peter J. Van Der Most</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Epidemiology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><affiliation wicri:level="1"><nlm:aff id="a28"><institution>Institute of Genetic Epidemiology, Helmholtz Zentrum München—German Research Center for Environmental Health</institution>, Neuherberg 85764,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a29"><institution>Department of Medicine, University Hospital Munich, Ludwig-Maximilians-University</institution>, Munich 80539,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a30"><institution>DZHK (German Centre for Cardiovascular Research), Partner site Munich Heart Alliance</institution>, Munich 80336,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nivard, Michel" sort="Nivard, Michel" uniqKey="Nivard M" first="Michel" last="Nivard">Michel Nivard</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a31"><institution>EMGO+ Institute for Health and Care Research, VU University & VU University Medical Center</institution>, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Salvi, Erika" sort="Salvi, Erika" uniqKey="Salvi E" first="Erika" last="Salvi">Erika Salvi</name><affiliation wicri:level="1"><nlm:aff id="a32"><institution>Department of Health Sciences, University of Milano</institution>, Milano 20122,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Stewart, James D" sort="Stewart, James D" uniqKey="Stewart J" first="James D." last="Stewart">James D. Stewart</name><affiliation wicri:level="1"><nlm:aff id="a9"><institution>Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a33"><institution>Carolina Population Center, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Thayer, Julian F" sort="Thayer, Julian F" uniqKey="Thayer J" first="Julian F." last="Thayer">Julian F. Thayer</name><affiliation wicri:level="1"><nlm:aff id="a34"><institution>Department of Psychology, The Ohio State University</institution>, 1835 Neil Avenue, Columbus, Ohio 43210,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Verweij, Niek" sort="Verweij, Niek" uniqKey="Verweij N" first="Niek" last="Verweij">Niek Verweij</name><affiliation wicri:level="1"><nlm:aff id="a35"><institution>Department of Cardiology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Wong, Andrew" sort="Wong, Andrew" uniqKey="Wong A" first="Andrew" last="Wong">Andrew Wong</name><affiliation wicri:level="1"><nlm:aff id="a36"><institution>MRC Unit for Lifelong Health and Ageing, University College London</institution>, 33 Bedford Place, London WC1B 5JU,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zabaneh, Delilah" sort="Zabaneh, Delilah" uniqKey="Zabaneh D" first="Delilah" last="Zabaneh">Delilah Zabaneh</name><affiliation wicri:level="1"><nlm:aff id="a37"><institution>Institute of Psychiatry, Psychology & Neuroscience, King's College London</institution>, De Crespigny Park, London SE5 8AF,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a38"><institution>University College London Genetics Institute, University College London</institution>, London WC1E 6BT,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zafarmand, Mohammad H" sort="Zafarmand, Mohammad H" uniqKey="Zafarmand M" first="Mohammad H." last="Zafarmand">Mohammad H. Zafarmand</name><affiliation wicri:level="1"><nlm:aff id="a39"><institution>Department of Public Health, Academic Medical Center (AMC), University of Amsterdam</institution>, Amsterdam 1105 AZ,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a40"><institution>Department of Obstetrics and Gynaecology, Academic Medical Centre, University of Amsterdam</institution>, Amsterdam 1105 AZ,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Abdellaoui, Abdel" sort="Abdellaoui, Abdel" uniqKey="Abdellaoui A" first="Abdel" last="Abdellaoui">Abdel Abdellaoui</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a31"><institution>EMGO+ Institute for Health and Care Research, VU University & VU University Medical Center</institution>, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Albarwani, Sulayma" sort="Albarwani, Sulayma" uniqKey="Albarwani S" first="Sulayma" last="Albarwani">Sulayma Albarwani</name><affiliation><nlm:aff id="a41"><institution>Department of Physiology, College of Medicine and Health Sciences, Sultan Qaboos University</institution>, Muscat Al-Khoudh 123,<country>Sultanate of Oman</country></nlm:aff><wicri:noCountry code="nlm country">Sultanate of Oman</wicri:noCountry></affiliation></author><author><name sortKey="Albert, Christine" sort="Albert, Christine" uniqKey="Albert C" first="Christine" last="Albert">Christine Albert</name><affiliation wicri:level="1"><nlm:aff id="a42"><institution>Brigham and Women's Hospital, Harvard Medical School</institution>, Boston, Massachusetts 02115,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Alonso, Alvaro" sort="Alonso, Alvaro" uniqKey="Alonso A" first="Alvaro" last="Alonso">Alvaro Alonso</name><affiliation wicri:level="1"><nlm:aff id="a43"><institution>Department of Epidemiology, Rollins School of Public Health, Emory University</institution>, Atlanta, Georgia 30322,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ashar, Foram" sort="Ashar, Foram" uniqKey="Ashar F" first="Foram" last="Ashar">Foram Ashar</name><affiliation wicri:level="1"><nlm:aff id="a44"><institution>McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine</institution>, Baltimore, Maryland 21205,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Auvinen, Juha" sort="Auvinen, Juha" uniqKey="Auvinen J" first="Juha" last="Auvinen">Juha Auvinen</name><affiliation wicri:level="1"><nlm:aff id="a19"><institution>Center for Life Course Health Research, University of Oulu</institution>, Oulu 90014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a45"><institution>Unit of Primary Health Care, Oulu University Hospital</institution>, Oulu 90220,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Axelsson, Tomas" sort="Axelsson, Tomas" uniqKey="Axelsson T" first="Tomas" last="Axelsson">Tomas Axelsson</name><affiliation wicri:level="1"><nlm:aff id="a46"><institution>Department of Medical Sciences, Molecular Medicine, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Baker, Dewleen G" sort="Baker, Dewleen G" uniqKey="Baker D" first="Dewleen G." last="Baker">Dewleen G. Baker</name><affiliation wicri:level="1"><nlm:aff id="a27"><institution>Center for Stress and Mental Health (CESAMH), VA San Diego Healthcare System</institution>, San Diego, California 92161,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a26"><institution>Department of Psychiatry, University of California, San Diego</institution>, San Diego, California 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Bakker, Paul I W" sort="De Bakker, Paul I W" uniqKey="De Bakker P" first="Paul I. W." last="De Bakker">Paul I. W. De Bakker</name><affiliation wicri:level="1"><nlm:aff id="a47"><institution>Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht</institution>, Utrecht 3584 CX,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a48"><institution>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht</institution>, Utrecht,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Barcella, Matteo" sort="Barcella, Matteo" uniqKey="Barcella M" first="Matteo" last="Barcella">Matteo Barcella</name><affiliation wicri:level="1"><nlm:aff id="a32"><institution>Department of Health Sciences, University of Milano</institution>, Milano 20122,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bayoumi, Riad" sort="Bayoumi, Riad" uniqKey="Bayoumi R" first="Riad" last="Bayoumi">Riad Bayoumi</name><affiliation wicri:level="1"><nlm:aff id="a49"><institution>College of Medicine, Mohammed Bin Rashid University</institution>, PO Box 505055, Dubai Healthcare City,<country>United Arab Emirates</country></nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bieringa, Rob J" sort="Bieringa, Rob J" uniqKey="Bieringa R" first="Rob J." last="Bieringa">Rob J. Bieringa</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Epidemiology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Boomsma, Dorret" sort="Boomsma, Dorret" uniqKey="Boomsma D" first="Dorret" last="Boomsma">Dorret Boomsma</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a31"><institution>EMGO+ Institute for Health and Care Research, VU University & VU University Medical Center</institution>, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Boucher, Gabrielle" sort="Boucher, Gabrielle" uniqKey="Boucher G" first="Gabrielle" last="Boucher">Gabrielle Boucher</name><affiliation wicri:level="1"><nlm:aff id="a15"><institution>Montreal Heart Institute</institution>, Montreal, Quebec,<country>Canada</country> H1T 1C8</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Britton, Annie R" sort="Britton, Annie R" uniqKey="Britton A" first="Annie R." last="Britton">Annie R. Britton</name><affiliation wicri:level="1"><nlm:aff id="a50"><institution>Department of Epidemiology and Public Health, University College London</institution>, London WC1E 6BT,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Christophersen, Ingrid" sort="Christophersen, Ingrid" uniqKey="Christophersen I" first="Ingrid" last="Christophersen">Ingrid Christophersen</name><affiliation wicri:level="1"><nlm:aff id="a51"><institution>Cardiovascular Research Center, Massachusetts General Hospital</institution>, Boston, Massachusetts 02114,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a52"><institution>Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT</institution>, Cambridge, Massachusetts 02114,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a53"><institution>Department of Medical Research, Bærum Hospital, Vestre Viken Hospital Trust</institution>, Rud 1346,<country>Norway</country></nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Dietrich, Andrea" sort="Dietrich, Andrea" uniqKey="Dietrich A" first="Andrea" last="Dietrich">Andrea Dietrich</name><affiliation wicri:level="1"><nlm:aff id="a54"><institution>Department of Child- and Adolescent Psychiatry, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ehret, George B" sort="Ehret, George B" uniqKey="Ehret G" first="George B." last="Ehret">George B. Ehret</name><affiliation wicri:level="1"><nlm:aff id="a55"><institution>Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine</institution>, Baltimore, Maryland 21205,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a56"><institution>Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospital</institution>, Geneva 1211,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ellinor, Patrick T" sort="Ellinor, Patrick T" uniqKey="Ellinor P" first="Patrick T." last="Ellinor">Patrick T. Ellinor</name><affiliation wicri:level="1"><nlm:aff id="a52"><institution>Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT</institution>, Cambridge, Massachusetts 02114,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a57"><institution>Cardiac Arrhythmia Service & Cardiovascular Research Center, Massachusetts General Hospital</institution>, Boston, Massachusetts 02114,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Eskola, Markku" sort="Eskola, Markku" uniqKey="Eskola M" first="Markku" last="Eskola">Markku Eskola</name><affiliation wicri:level="1"><nlm:aff id="a18"><institution>Department of Cardiology, Heart Hospital, Tampere University Hospital</institution>, Tampere 33521,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a58"><institution>Department of Cardiology, University of Tampere School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Felix, Janine F" sort="Felix, Janine F" uniqKey="Felix J" first="Janine F." last="Felix">Janine F. Felix</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Floras, John S" sort="Floras, John S" uniqKey="Floras J" first="John S." last="Floras">John S. Floras</name><affiliation wicri:level="1"><nlm:aff id="a59"><institution>University Health Network and Mount Sinai Hospital Division of Cardiology, Department of Medicine, University of Toronto</institution>, Ontario,<country>Canada</country> M5S</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a60"><institution>Toronto General Research Institute, University Health Network</institution>, Toronto,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H." last="Franco">Oscar H. Franco</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Friberg, Peter" sort="Friberg, Peter" uniqKey="Friberg P" first="Peter" last="Friberg">Peter Friberg</name><affiliation wicri:level="1"><nlm:aff id="a61"><institution>Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska University Hospital, University of Gothenburg</institution>, Gothenburg,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gademan, Maaike G J" sort="Gademan, Maaike G J" uniqKey="Gademan M" first="Maaike G. J." last="Gademan">Maaike G. J. Gademan</name><affiliation wicri:level="1"><nlm:aff id="a39"><institution>Department of Public Health, Academic Medical Center (AMC), University of Amsterdam</institution>, Amsterdam 1105 AZ,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Geyer, Mark A" sort="Geyer, Mark A" uniqKey="Geyer M" first="Mark A." last="Geyer">Mark A. Geyer</name><affiliation wicri:level="1"><nlm:aff id="a26"><institution>Department of Psychiatry, University of California, San Diego</institution>, San Diego, California 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Giedraitis, Vilmantas" sort="Giedraitis, Vilmantas" uniqKey="Giedraitis V" first="Vilmantas" last="Giedraitis">Vilmantas Giedraitis</name><affiliation wicri:level="1"><nlm:aff id="a62"><institution>Department of Public Health and Caring Sciences, Molecular Geriatrics, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hartman, Catharina A" sort="Hartman, Catharina A" uniqKey="Hartman C" first="Catharina A." last="Hartman">Catharina A. Hartman</name><affiliation wicri:level="1"><nlm:aff id="a63"><institution>Interdisciplinary Center Psychopathology and Emotion regulation, Department of Psychiatry, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hemerich, Daiane" sort="Hemerich, Daiane" uniqKey="Hemerich D" first="Daiane" last="Hemerich">Daiane Hemerich</name><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht</institution>, Heidelberglaan 100, Utrecht 3584CX,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a64"><institution>CAPES Foundation, Ministry of Education of Brazil</institution>, Brasília DF 70040-020,<country>Brazil</country></nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a31"><institution>EMGO+ Institute for Health and Care Research, VU University & VU University Medical Center</institution>, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Huikuri, Heikki" sort="Huikuri, Heikki" uniqKey="Huikuri H" first="Heikki" last="Huikuri">Heikki Huikuri</name><affiliation wicri:level="1"><nlm:aff id="a65"><institution>Research Unit of Internal Medicine, Medical Research Center Oulu, Oulu University Hospital and University of Oulu</institution>, Oulu 90220,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hutri K Honen, Nina" sort="Hutri K Honen, Nina" uniqKey="Hutri K Honen N" first="Nina" last="Hutri-K Hönen">Nina Hutri-K Hönen</name><affiliation wicri:level="1"><nlm:aff id="a66"><institution>Department of Pediatrics, Tampere University Hospital</institution>, Tampere 33521,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a67"><institution>Department of Pediatrics, University of Tampere School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Jouven, Xavier" sort="Jouven, Xavier" uniqKey="Jouven X" first="Xavier" last="Jouven">Xavier Jouven</name><affiliation wicri:level="1"><nlm:aff id="a68"><institution>INSERM U970, Paris Descartes University</institution>, Paris 75006,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Junttila, Juhani" sort="Junttila, Juhani" uniqKey="Junttila J" first="Juhani" last="Junttila">Juhani Junttila</name><affiliation wicri:level="1"><nlm:aff id="a65"><institution>Research Unit of Internal Medicine, Medical Research Center Oulu, Oulu University Hospital and University of Oulu</institution>, Oulu 90220,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Juonala, Markus" sort="Juonala, Markus" uniqKey="Juonala M" first="Markus" last="Juonala">Markus Juonala</name><affiliation wicri:level="1"><nlm:aff id="a69"><institution>Department of Medicine, University of Turku</institution>, Turku 20520,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a70"><institution>Division of Medicine, Turku University Hospital</institution>, Turku 20521,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kiviniemi, Antti M" sort="Kiviniemi, Antti M" uniqKey="Kiviniemi A" first="Antti M." last="Kiviniemi">Antti M. Kiviniemi</name><affiliation wicri:level="1"><nlm:aff id="a65"><institution>Research Unit of Internal Medicine, Medical Research Center Oulu, Oulu University Hospital and University of Oulu</institution>, Oulu 90220,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kors, Jan A" sort="Kors, Jan A" uniqKey="Kors J" first="Jan A." last="Kors">Jan A. Kors</name><affiliation wicri:level="1"><nlm:aff id="a71"><institution>Department of Medical Informatics, Erasmus Medical Center</institution>, Rotterdam 3015 CE,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name><affiliation wicri:level="1"><nlm:aff id="a50"><institution>Department of Epidemiology and Public Health, University College London</institution>, London WC1E 6BT,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a72"><institution>ISER, Essex University</institution>, Colchester, Essex CO4 3SQ,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kuznetsova, Tatiana" sort="Kuznetsova, Tatiana" uniqKey="Kuznetsova T" first="Tatiana" last="Kuznetsova">Tatiana Kuznetsova</name><affiliation wicri:level="1"><nlm:aff id="a73"><institution>Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven</institution>, Leuven 3000,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Laurie, Cathy C" sort="Laurie, Cathy C" uniqKey="Laurie C" first="Cathy C." last="Laurie">Cathy C. Laurie</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lefrandt, Joop D" sort="Lefrandt, Joop D" uniqKey="Lefrandt J" first="Joop D." last="Lefrandt">Joop D. Lefrandt</name><affiliation wicri:level="1"><nlm:aff id="a74"><institution>Department of Internal Medicine, Division of Vascular Medicine, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Li, Yong" sort="Li, Yong" uniqKey="Li Y" first="Yong" last="Li">Yong Li</name><affiliation wicri:level="1"><nlm:aff id="a75"><institution>Division of Genetic Epidemiology, Institute for Medical Biometry and Statistics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg</institution>, Freiburg 79110,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Li, Yun" sort="Li, Yun" uniqKey="Li Y" first="Yun" last="Li">Yun Li</name><affiliation wicri:level="1"><nlm:aff id="a76"><institution>Department of Genetics, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a77"><institution>Department of Biostatistics, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a78"><institution>Department of Computer Science, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Liao, Duanping" sort="Liao, Duanping" uniqKey="Liao D" first="Duanping" last="Liao">Duanping Liao</name><affiliation wicri:level="1"><nlm:aff id="a79"><institution>Division of Epidemiology, Department of Public Health Sciences, Penn State University College of Medicine</institution>, Hershey, Pennsylvania 17033,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Limacher, Marian C" sort="Limacher, Marian C" uniqKey="Limacher M" first="Marian C." last="Limacher">Marian C. Limacher</name><affiliation wicri:level="1"><nlm:aff id="a80"><institution>Division of Cardiovascular Medicine, University of Florida College of Medicine</institution>, Gainesville, Florida 32611,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lin, Henry J" sort="Lin, Henry J" uniqKey="Lin H" first="Henry J." last="Lin">Henry J. Lin</name><affiliation wicri:level="1"><nlm:aff id="a81"><institution>Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center</institution>, Torrance, California 90502,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a82"><institution>Division of Medical Genetics, Department of Pediatrics, Harbor-UCLA Medical Center</institution>, Torrance, California 90502,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lindgren, Cecilia M" sort="Lindgren, Cecilia M" uniqKey="Lindgren C" first="Cecilia M." last="Lindgren">Cecilia M. Lindgren</name><affiliation wicri:level="1"><nlm:aff id="a83"><institution>Li Ka Shing Centre for Health Information and Discovery, The Big Data Institute, University of Oxford</institution>, Oxford OX3 7BN,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a84"><institution>Wellcome Trust Centre for Human Genetics, University of Oxford</institution>, Oxford OX3 7BN,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lubitz, Steven A" sort="Lubitz, Steven A" uniqKey="Lubitz S" first="Steven A." last="Lubitz">Steven A. Lubitz</name><affiliation wicri:level="1"><nlm:aff id="a52"><institution>Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT</institution>, Cambridge, Massachusetts 02114,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a57"><institution>Cardiac Arrhythmia Service & Cardiovascular Research Center, Massachusetts General Hospital</institution>, Boston, Massachusetts 02114,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mahajan, Anubha" sort="Mahajan, Anubha" uniqKey="Mahajan A" first="Anubha" last="Mahajan">Anubha Mahajan</name><affiliation wicri:level="1"><nlm:aff id="a84"><institution>Wellcome Trust Centre for Human Genetics, University of Oxford</institution>, Oxford OX3 7BN,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mcknight, Barbara" sort="Mcknight, Barbara" uniqKey="Mcknight B" first="Barbara" last="Mcknight">Barbara Mcknight</name><affiliation wicri:level="1"><nlm:aff id="a10"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>, Seattle, Washington 98104,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a85"><institution>Public Health Sciences Division, Fred Hutchinson Cancer Research Center</institution>, Seattle, Washington 98109,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zu Schwabedissen, Henriette Meyer" sort="Zu Schwabedissen, Henriette Meyer" uniqKey="Zu Schwabedissen H" first="Henriette Meyer" last="Zu Schwabedissen">Henriette Meyer Zu Schwabedissen</name><affiliation wicri:level="1"><nlm:aff id="a86"><institution>Biopharmacy, Department Pharmaceutical Sciences, University of Basel</institution>, Basel CH-4056,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Milaneschi, Yuri" sort="Milaneschi, Yuri" uniqKey="Milaneschi Y" first="Yuri" last="Milaneschi">Yuri Milaneschi</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Department of Psychiatry, EMGO Institute for Health and Care Research and Neuroscience Campus Amsterdam, VU University Medical Center/GGZ inGeest</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mononen, Nina" sort="Mononen, Nina" uniqKey="Mononen N" first="Nina" last="Mononen">Nina Mononen</name><affiliation wicri:level="1"><nlm:aff id="a16"><institution>Department of Clinical Chemistry, Fimlab Laboratories</institution>, Tampere 33520,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a17"><institution>Department of Clinical Chemistry, University of Tampere School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Morris, Andrew P" sort="Morris, Andrew P" uniqKey="Morris A" first="Andrew P." last="Morris">Andrew P. Morris</name><affiliation wicri:level="1"><nlm:aff id="a84"><institution>Wellcome Trust Centre for Human Genetics, University of Oxford</institution>, Oxford OX3 7BN,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a87"><institution>Department of Biostatistics, University of Liverpool</institution>, Liverpool L69 3GL,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nalls, Mike A" sort="Nalls, Mike A" uniqKey="Nalls M" first="Mike A." last="Nalls">Mike A. Nalls</name><affiliation wicri:level="1"><nlm:aff id="a88"><institution>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health</institution>, Bethesda, Maryland 20892,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Navis, Gerjan" sort="Navis, Gerjan" uniqKey="Navis G" first="Gerjan" last="Navis">Gerjan Navis</name><affiliation wicri:level="1"><nlm:aff id="a89"><institution>Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Neijts, Melanie" sort="Neijts, Melanie" uniqKey="Neijts M" first="Melanie" last="Neijts">Melanie Neijts</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a31"><institution>EMGO+ Institute for Health and Care Research, VU University & VU University Medical Center</institution>, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nikus, Kjell" sort="Nikus, Kjell" uniqKey="Nikus K" first="Kjell" last="Nikus">Kjell Nikus</name><affiliation wicri:level="1"><nlm:aff id="a18"><institution>Department of Cardiology, Heart Hospital, Tampere University Hospital</institution>, Tampere 33521,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a90"><institution>Department of Cardiology, University of Tampere, School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E." last="North">Kari E. North</name><affiliation wicri:level="1"><nlm:aff id="a9"><institution>Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a91"><institution>Carolina Center for Genome Sciences, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="O Connor, Daniel T" sort="O Connor, Daniel T" uniqKey="O Connor D" first="Daniel T." last="O'Connor">Daniel T. O'Connor</name><affiliation wicri:level="1"><nlm:aff id="a92"><institution>Department of Medicine, University of California, San Diego</institution>, San Diego, California 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ormel, Johan" sort="Ormel, Johan" uniqKey="Ormel J" first="Johan" last="Ormel">Johan Ormel</name><affiliation wicri:level="1"><nlm:aff id="a63"><institution>Interdisciplinary Center Psychopathology and Emotion regulation, Department of Psychiatry, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Perz, Siegfried" sort="Perz, Siegfried" uniqKey="Perz S" first="Siegfried" last="Perz">Siegfried Perz</name><affiliation wicri:level="1"><nlm:aff id="a93"><institution>Institute of Epidemiology II, Helmholtz Zentrum München—German Research Center for Environmental Health</institution>, Neuherberg 85764,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name><affiliation wicri:level="1"><nlm:aff id="a30"><institution>DZHK (German Centre for Cardiovascular Research), Partner site Munich Heart Alliance</institution>, Munich 80336,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a93"><institution>Institute of Epidemiology II, Helmholtz Zentrum München—German Research Center for Environmental Health</institution>, Neuherberg 85764,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a94"><institution>German Center for Diabetes Research</institution>, Neuherberg 85764,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M." last="Psaty">Bruce M. Psaty</name><affiliation wicri:level="1"><nlm:aff id="a10"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>, Seattle, Washington 98104,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a95"><institution>Departments of Epidemiology and Health Services, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a96"><institution>Group Health Research Institute, Group Health Cooperative</institution>, Seattle, Washington 98101,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Raitakari, Olli T" sort="Raitakari, Olli T" uniqKey="Raitakari O" first="Olli T." last="Raitakari">Olli T. Raitakari</name><affiliation wicri:level="1"><nlm:aff id="a97"><institution>Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital</institution>, Turku 20521,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a98"><institution>Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku</institution>, Turku 20520,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Risbrough, Victoria B" sort="Risbrough, Victoria B" uniqKey="Risbrough V" first="Victoria B." last="Risbrough">Victoria B. Risbrough</name><affiliation wicri:level="1"><nlm:aff id="a26"><institution>Department of Psychiatry, University of California, San Diego</institution>, San Diego, California 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a27"><institution>Center for Stress and Mental Health (CESAMH), VA San Diego Healthcare System</institution>, San Diego, California 92161,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sinner, Moritz F" sort="Sinner, Moritz F" uniqKey="Sinner M" first="Moritz F." last="Sinner">Moritz F. Sinner</name><affiliation wicri:level="1"><nlm:aff id="a29"><institution>Department of Medicine, University Hospital Munich, Ludwig-Maximilians-University</institution>, Munich 80539,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a30"><institution>DZHK (German Centre for Cardiovascular Research), Partner site Munich Heart Alliance</institution>, Munich 80336,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Siscovick, David" sort="Siscovick, David" uniqKey="Siscovick D" first="David" last="Siscovick">David Siscovick</name><affiliation wicri:level="1"><nlm:aff id="a99"><institution>The New York Academy of Medicine</institution>, New York, New York 10029,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Smit, Johannes H" sort="Smit, Johannes H" uniqKey="Smit J" first="Johannes H." last="Smit">Johannes H. Smit</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Department of Psychiatry, EMGO Institute for Health and Care Research and Neuroscience Campus Amsterdam, VU University Medical Center/GGZ inGeest</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Smith, Nicholas L" sort="Smith, Nicholas L" uniqKey="Smith N" first="Nicholas L." last="Smith">Nicholas L. Smith</name><affiliation wicri:level="1"><nlm:aff id="a96"><institution>Group Health Research Institute, Group Health Cooperative</institution>, Seattle, Washington 98101,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a100"><institution>Department of Epidemiology, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a101"><institution>Seattle Epidemiologic Research and Information Center, Veterans Affairs Office of Research and Development</institution>, Seattle, Washington 98108,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Soliman, Elsayed Z" sort="Soliman, Elsayed Z" uniqKey="Soliman E" first="Elsayed Z." last="Soliman">Elsayed Z. Soliman</name><affiliation wicri:level="1"><nlm:aff id="a102"><institution>Epidemiological Cardiology Research Center (EPICARE), Division of Public Health Sciences, Wake Forest School of Medicine</institution>, Winston-Salem, North Carolina 27157,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sotoodehnia, Nona" sort="Sotoodehnia, Nona" uniqKey="Sotoodehnia N" first="Nona" last="Sotoodehnia">Nona Sotoodehnia</name><affiliation wicri:level="1"><nlm:aff id="a103"><institution>Cardiovascular Health Research Unit, Division of Cardiology, Departments of Medicine and Epidemiology, University of Washington</institution>, Seattle, Washington 98101,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Staessen, Jan A" sort="Staessen, Jan A" uniqKey="Staessen J" first="Jan A." last="Staessen">Jan A. Staessen</name><affiliation wicri:level="1"><nlm:aff id="a73"><institution>Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven</institution>, Leuven 3000,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Stein, Phyllis K" sort="Stein, Phyllis K" uniqKey="Stein P" first="Phyllis K." last="Stein">Phyllis K. Stein</name><affiliation wicri:level="1"><nlm:aff id="a104"><institution>Heart Rate Variability Lab, Washington University School of Medicine</institution>, St Louis, Missouri 63108,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Stilp, Adrienne M" sort="Stilp, Adrienne M" uniqKey="Stilp A" first="Adrienne M." last="Stilp">Adrienne M. Stilp</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Stolarz Skrzypek, Katarzyna" sort="Stolarz Skrzypek, Katarzyna" uniqKey="Stolarz Skrzypek K" first="Katarzyna" last="Stolarz-Skrzypek">Katarzyna Stolarz-Skrzypek</name><affiliation wicri:level="1"><nlm:aff id="a105"><institution>First Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College</institution>, Cracow 31-008,<country>Poland</country></nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name><affiliation wicri:level="1"><nlm:aff id="a28"><institution>Institute of Genetic Epidemiology, Helmholtz Zentrum München—German Research Center for Environmental Health</institution>, Neuherberg 85764,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a106"><institution>Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität</institution>, Munich 81377,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sundstrom, Johan" sort="Sundstrom, Johan" uniqKey="Sundstrom J" first="Johan" last="Sundström">Johan Sundström</name><affiliation wicri:level="1"><nlm:aff id="a107"><institution>Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University</institution>, Uppsala 751 85,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Swenne, Cees A" sort="Swenne, Cees A" uniqKey="Swenne C" first="Cees A." last="Swenne">Cees A. Swenne</name><affiliation wicri:level="1"><nlm:aff id="a108"><institution>Department of Cardiology, Leiden University Medical Center</institution>, Leiden 2300 RC,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Syv Nen, Ann Christine" sort="Syv Nen, Ann Christine" uniqKey="Syv Nen A" first="Ann-Christine" last="Syv Nen">Ann-Christine Syv Nen</name><affiliation wicri:level="1"><nlm:aff id="a46"><institution>Department of Medical Sciences, Molecular Medicine, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tardif, Jean Claude" sort="Tardif, Jean Claude" uniqKey="Tardif J" first="Jean-Claude" last="Tardif">Jean-Claude Tardif</name><affiliation wicri:level="1"><nlm:aff id="a15"><institution>Montreal Heart Institute</institution>, Montreal, Quebec,<country>Canada</country> H1T 1C8</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a109"><institution>Université de Montréal</institution>, Montreal, Quebec,<country>Canada</country> H3T IJ4</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Taylor, Kent D" sort="Taylor, Kent D" uniqKey="Taylor K" first="Kent D." last="Taylor">Kent D. Taylor</name><affiliation wicri:level="1"><nlm:aff id="a110"><institution>Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center</institution>, Torrance, California 90509,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><affiliation wicri:level="1"><nlm:aff id="a111"><institution>Institute for Community Medicine, University Medicine Greifswald</institution>, Greifswald 17475,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Thornton, Timothy A" sort="Thornton, Timothy A" uniqKey="Thornton T" first="Timothy A." last="Thornton">Timothy A. Thornton</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tinker, Lesley E" sort="Tinker, Lesley E" uniqKey="Tinker L" first="Lesley E." last="Tinker">Lesley E. Tinker</name><affiliation wicri:level="1"><nlm:aff id="a85"><institution>Public Health Sciences Division, Fred Hutchinson Cancer Research Center</institution>, Seattle, Washington 98109,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G." last="Uitterlinden">André G. Uitterlinden</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a112"><institution>Department of Internal Medicine, Erasmus University Medical Center</institution>, Rotterdam 3015 CE,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a113"><institution>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging NCHA)</institution>, Leiden 2300 RC,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Van Setten, Jessica" sort="Van Setten, Jessica" uniqKey="Van Setten J" first="Jessica" last="Van Setten">Jessica Van Setten</name><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht</institution>, Heidelberglaan 100, Utrecht 3584CX,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Voss, Andreas" sort="Voss, Andreas" uniqKey="Voss A" first="Andreas" last="Voss">Andreas Voss</name><affiliation wicri:level="1"><nlm:aff id="a114"><institution>Institute of Innovative Health Technologies—IGHT Jena Ernst-Abbe-Hochschule Jena</institution>, Jena 07745,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Waldenberger, Melanie" sort="Waldenberger, Melanie" uniqKey="Waldenberger M" first="Melanie" last="Waldenberger">Melanie Waldenberger</name><affiliation wicri:level="1"><nlm:aff id="a93"><institution>Institute of Epidemiology II, Helmholtz Zentrum München—German Research Center for Environmental Health</institution>, Neuherberg 85764,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a115"><institution>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München—German Research Center for Environmental Health</institution>, Neuherberg 85764,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Wilhelmsen, Kirk C" sort="Wilhelmsen, Kirk C" uniqKey="Wilhelmsen K" first="Kirk C." last="Wilhelmsen">Kirk C. Wilhelmsen</name><affiliation wicri:level="1"><nlm:aff id="a116"><institution>Departments of Genetics and Neurology University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a117"><institution>The Renaissance Computing Institute</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a31"><institution>EMGO+ Institute for Health and Care Research, VU University & VU University Medical Center</institution>, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Wong, Quenna" sort="Wong, Quenna" uniqKey="Wong Q" first="Quenna" last="Wong">Quenna Wong</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Zhu Ming" sort="Zhang, Zhu Ming" uniqKey="Zhang Z" first="Zhu-Ming" last="Zhang">Zhu-Ming Zhang</name><affiliation wicri:level="1"><nlm:aff id="a102"><institution>Epidemiological Cardiology Research Center (EPICARE), Division of Public Health Sciences, Wake Forest School of Medicine</institution>, Winston-Salem, North Carolina 27157,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a118"><institution>Department of Epidemiology & Prevention, Division of Public Health Sciences, Wake Forest School of Medicine</institution>, Winston-Salem, North Carolina 27157,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zonderman, Alan B" sort="Zonderman, Alan B" uniqKey="Zonderman A" first="Alan B." last="Zonderman">Alan B. Zonderman</name><affiliation wicri:level="1"><nlm:aff id="a119"><institution>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health</institution>, Baltimore, Maryland 21224,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Cusi, Daniele" sort="Cusi, Daniele" uniqKey="Cusi D" first="Daniele" last="Cusi">Daniele Cusi</name><affiliation wicri:level="1"><nlm:aff id="a120"><institution>Institute of Biomedical Technologies, CNR—Italian National Research Council</institution>, Milan 20090,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a121"><institution>KOS Genetic SRL</institution>, Bresso (Milano) 20091,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Evans, Michele K" sort="Evans, Michele K" uniqKey="Evans M" first="Michele K." last="Evans">Michele K. Evans</name><affiliation wicri:level="1"><nlm:aff id="a119"><institution>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health</institution>, Baltimore, Maryland 21224,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Greiser, Halina K" sort="Greiser, Halina K" uniqKey="Greiser H" first="Halina K." last="Greiser">Halina K. Greiser</name><affiliation wicri:level="1"><nlm:aff id="a122"><institution>German Cancer Research Centre, Division of Cancer Epidemiology</institution>, Heidelberg 69210,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Harst, Pim" sort="Van Der Harst, Pim" uniqKey="Van Der Harst P" first="Pim" last="Van Der Harst">Pim Van Der Harst</name><affiliation wicri:level="1"><nlm:aff id="a35"><institution>Department of Cardiology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hassan, Mohammad" sort="Hassan, Mohammad" uniqKey="Hassan M" first="Mohammad" last="Hassan">Mohammad Hassan</name><affiliation><nlm:aff id="a41"><institution>Department of Physiology, College of Medicine and Health Sciences, Sultan Qaboos University</institution>, Muscat Al-Khoudh 123,<country>Sultanate of Oman</country></nlm:aff><wicri:noCountry code="nlm country">Sultanate of Oman</wicri:noCountry></affiliation></author><author><name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Department of Medical Sciences, Molecular Epidemiology, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a8"><institution>Science for Life Laboratory, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a123"><institution>Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine</institution>, Stanford, California 94305,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name><affiliation wicri:level="1"><nlm:aff id="a19"><institution>Center for Life Course Health Research, University of Oulu</institution>, Oulu 90014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a45"><institution>Unit of Primary Health Care, Oulu University Hospital</institution>, Oulu 90220,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a124"><institution>Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, St Mary’s campus, Imperial College London</institution>, London W2 1PG,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a125"><institution>Biocenter Oulu University of Oulu</institution>, Oulu 90014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="K B, Stefan" sort="K B, Stefan" uniqKey="K B S" first="Stefan" last="K B">Stefan K B</name><affiliation wicri:level="1"><nlm:aff id="a29"><institution>Department of Medicine, University Hospital Munich, Ludwig-Maximilians-University</institution>, Munich 80539,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a30"><institution>DZHK (German Centre for Cardiovascular Research), Partner site Munich Heart Alliance</institution>, Munich 80336,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="K Honen, Mika" sort="K Honen, Mika" uniqKey="K Honen M" first="Mika" last="K Hönen">Mika K Hönen</name><affiliation wicri:level="1"><nlm:aff id="a126"><institution>Department of Clinical Physiology, Tampere University Hospital</institution>, Tampere 33521,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a127"><institution>Department of Clinical Physiology, University of Tampere, School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kivimaki, Mika" sort="Kivimaki, Mika" uniqKey="Kivimaki M" first="Mika" last="Kivimaki">Mika Kivimaki</name><affiliation wicri:level="1"><nlm:aff id="a50"><institution>Department of Epidemiology and Public Health, University College London</institution>, London WC1E 6BT,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kooperberg, Charles" sort="Kooperberg, Charles" uniqKey="Kooperberg C" first="Charles" last="Kooperberg">Charles Kooperberg</name><affiliation wicri:level="1"><nlm:aff id="a85"><institution>Public Health Sciences Division, Fred Hutchinson Cancer Research Center</institution>, Seattle, Washington 98109,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kuh, Diana" sort="Kuh, Diana" uniqKey="Kuh D" first="Diana" last="Kuh">Diana Kuh</name><affiliation wicri:level="1"><nlm:aff id="a36"><institution>MRC Unit for Lifelong Health and Ageing, University College London</institution>, 33 Bedford Place, London WC1B 5JU,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name><affiliation wicri:level="1"><nlm:aff id="a16"><institution>Department of Clinical Chemistry, Fimlab Laboratories</institution>, Tampere 33520,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a17"><institution>Department of Clinical Chemistry, University of Tampere School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name><affiliation wicri:level="1"><nlm:aff id="a107"><institution>Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University</institution>, Uppsala 751 85,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nievergelt, Caroline M" sort="Nievergelt, Caroline M" uniqKey="Nievergelt C" first="Caroline M." last="Nievergelt">Caroline M. Nievergelt</name><affiliation wicri:level="1"><nlm:aff id="a26"><institution>Department of Psychiatry, University of California, San Diego</institution>, San Diego, California 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a27"><institution>Center for Stress and Mental Health (CESAMH), VA San Diego Healthcare System</institution>, San Diego, California 92161,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="O Donnell, Chris J" sort="O Donnell, Chris J" uniqKey="O Donnell C" first="Chris J." last="O'Donnell">Chris J. O'Donnell</name><affiliation wicri:level="1"><nlm:aff id="a20"><institution>Framingham Heart Study</institution>, Framingham, Massachusetts 01702,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a21"><institution>Population Sciences Branch, National Heart, Lung and Blood Institute</institution>, Bethesda, Maryland 20892,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a128"><institution>Cardiology Section, Boston Veteran’s Administration Healthcare</institution>, Boston, Maryland 02132,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Oldehinkel, Albertine J" sort="Oldehinkel, Albertine J" uniqKey="Oldehinkel A" first="Albertine J." last="Oldehinkel">Albertine J. Oldehinkel</name><affiliation wicri:level="1"><nlm:aff id="a63"><institution>Interdisciplinary Center Psychopathology and Emotion regulation, Department of Psychiatry, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Penninx, Brenda" sort="Penninx, Brenda" uniqKey="Penninx B" first="Brenda" last="Penninx">Brenda Penninx</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Department of Psychiatry, EMGO Institute for Health and Care Research and Neuroscience Campus Amsterdam, VU University Medical Center/GGZ inGeest</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Reiner, Alexander P" sort="Reiner, Alexander P" uniqKey="Reiner A" first="Alexander P." last="Reiner">Alexander P. Reiner</name><affiliation wicri:level="1"><nlm:aff id="a85"><institution>Public Health Sciences Division, Fred Hutchinson Cancer Research Center</institution>, Seattle, Washington 98109,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a100"><institution>Department of Epidemiology, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Riese, Harriette" sort="Riese, Harriette" uniqKey="Riese H" first="Harriëtte" last="Riese">Harriëtte Riese</name><affiliation wicri:level="1"><nlm:aff id="a63"><institution>Interdisciplinary Center Psychopathology and Emotion regulation, Department of Psychiatry, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Van Roon, Arie M" sort="Van Roon, Arie M" uniqKey="Van Roon A" first="Arie M." last="Van Roon">Arie M. Van Roon</name><affiliation wicri:level="1"><nlm:aff id="a74"><institution>Department of Internal Medicine, Division of Vascular Medicine, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Rioux, John D" sort="Rioux, John D" uniqKey="Rioux J" first="John D." last="Rioux">John D. Rioux</name><affiliation wicri:level="1"><nlm:aff id="a15"><institution>Montreal Heart Institute</institution>, Montreal, Quebec,<country>Canada</country> H1T 1C8</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a109"><institution>Université de Montréal</institution>, Montreal, Quebec,<country>Canada</country> H3T IJ4</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I." last="Rotter">Jerome I. Rotter</name><affiliation wicri:level="1"><nlm:aff id="a110"><institution>Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center</institution>, Torrance, California 90509,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sofer, Tamar" sort="Sofer, Tamar" uniqKey="Sofer T" first="Tamar" last="Sofer">Tamar Sofer</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Stricker, Bruno H" sort="Stricker, Bruno H" uniqKey="Stricker B" first="Bruno H." last="Stricker">Bruno H. Stricker</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a129"><institution>Inspectorate for Health Care</institution>, The Hague 2511 VX,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tiemeier, Henning" sort="Tiemeier, Henning" uniqKey="Tiemeier H" first="Henning" last="Tiemeier">Henning Tiemeier</name><affiliation wicri:level="1"><nlm:aff id="a11"><institution>Department of Child and Adolescent Psychiatry/Psychology, Department of Child and Adolescent Psychiatry</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Vrijkotte, Tanja G M" sort="Vrijkotte, Tanja G M" uniqKey="Vrijkotte T" first="Tanja G. M." last="Vrijkotte">Tanja G. M. Vrijkotte</name><affiliation wicri:level="1"><nlm:aff id="a39"><institution>Department of Public Health, Academic Medical Center (AMC), University of Amsterdam</institution>, Amsterdam 1105 AZ,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Asselbergs, Folkert W" sort="Asselbergs, Folkert W" uniqKey="Asselbergs F" first="Folkert W." last="Asselbergs">Folkert W. Asselbergs</name><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht</institution>, Heidelberglaan 100, Utrecht 3584CX,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a130"><institution>Institute of Cardiovascular Science, University College London</institution>, 222 Euston Road, London NW1 2DA,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a131"><institution>Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute</institution>, Utrecht 3501 DG,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Brundel, Bianca J J M" sort="Brundel, Bianca J J M" uniqKey="Brundel B" first="Bianca J. J. M." last="Brundel">Bianca J. J. M. Brundel</name><affiliation wicri:level="1"><nlm:aff id="a132"><institution>Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center</institution>, De Boelelaan 1118, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Heckbert, Susan R" sort="Heckbert, Susan R" uniqKey="Heckbert S" first="Susan R." last="Heckbert">Susan R. Heckbert</name><affiliation wicri:level="1"><nlm:aff id="a10"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>, Seattle, Washington 98104,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a100"><institution>Department of Epidemiology, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Whitsel, Eric A" sort="Whitsel, Eric A" uniqKey="Whitsel E" first="Eric A." last="Whitsel">Eric A. Whitsel</name><affiliation wicri:level="1"><nlm:aff id="a9"><institution>Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a133"><institution>Department of Medicine, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Den Hoed, Marcel" sort="Den Hoed, Marcel" uniqKey="Den Hoed M" first="Marcel" last="Den Hoed">Marcel Den Hoed</name><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Department of Medical Sciences, Molecular Epidemiology, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a8"><institution>Science for Life Laboratory, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Snieder, Harold" sort="Snieder, Harold" uniqKey="Snieder H" first="Harold" last="Snieder">Harold Snieder</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Epidemiology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Geus, Eco J C" sort="De Geus, Eco J C" uniqKey="De Geus E" first="Eco J. C." last="De Geus">Eco J. C. De Geus</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a31"><institution>EMGO+ Institute for Health and Care Research, VU University & VU University Medical Center</institution>, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28613276</idno><idno type="pmc">5474732</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474732</idno><idno type="RBID">PMC:5474732</idno><idno type="doi">10.1038/ncomms15805</idno><date when="2017">2017</date><idno type="wicri:Area/Pmc/Corpus">000797</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000797</idno><idno type="wicri:Area/Pmc/Curation">000796</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000796</idno><idno type="wicri:Area/Pmc/Checkpoint">000296</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000296</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">000A24</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000A24</idno><idno type="wicri:Area/PubMed/Curation">000A21</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000A21</idno><idno type="wicri:Area/PubMed/Checkpoint">000A21</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000A21</idno><idno type="wicri:Area/Ncbi/Merge">004976</idno><idno type="wicri:Area/Ncbi/Curation">004976</idno><idno type="wicri:Area/Ncbi/Checkpoint">004976</idno><idno type="wicri:Area/Main/Merge">000B69</idno><idno type="wicri:Area/Main/Curation">000B74</idno><idno type="wicri:Area/Main/Exploration">000B74</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Genetic loci associated with heart rate variability and their effects on cardiac disease risk</title><author><name sortKey="Nolte, Ilja M" sort="Nolte, Ilja M" uniqKey="Nolte I" first="Ilja M." last="Nolte">Ilja M. Nolte</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Epidemiology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Munoz, M Loretto" sort="Munoz, M Loretto" uniqKey="Munoz M" first="M. Loretto" last="Munoz">M. Loretto Munoz</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Epidemiology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tragante, Vinicius" sort="Tragante, Vinicius" uniqKey="Tragante V" first="Vinicius" last="Tragante">Vinicius Tragante</name><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht</institution>, Heidelberglaan 100, Utrecht 3584CX,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Amare, Azmeraw T" sort="Amare, Azmeraw T" uniqKey="Amare A" first="Azmeraw T." last="Amare">Azmeraw T. Amare</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Epidemiology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a3"><institution>Department of Epidemiology, School of Medicine, University of Adelaide</institution>, Adelaide, South Australia 5005,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a4"><institution>College of Medicine and Health Sciences, Bahir Dar University</institution>, Bahir Dar 6000,<country>Ethiopia</country></nlm:aff><country xml:lang="fr">Éthiopie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Jansen, Rick" sort="Jansen, Rick" uniqKey="Jansen R" first="Rick" last="Jansen">Rick Jansen</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Department of Psychiatry, EMGO Institute for Health and Care Research and Neuroscience Campus Amsterdam, VU University Medical Center/GGZ inGeest</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Vaez, Ahmad" sort="Vaez, Ahmad" uniqKey="Vaez A" first="Ahmad" last="Vaez">Ahmad Vaez</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Epidemiology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a6"><institution>School of Medicine, Isfahan University of Medical Sciences</institution>, Isfahan 81746-73461,<country>Iran</country></nlm:aff><country xml:lang="fr">Iran</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Von Der Heyde, Benedikt" sort="Von Der Heyde, Benedikt" uniqKey="Von Der Heyde B" first="Benedikt" last="Von Der Heyde">Benedikt Von Der Heyde</name><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Department of Medical Sciences, Molecular Epidemiology, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a8"><institution>Science for Life Laboratory, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Avery, Christy L" sort="Avery, Christy L" uniqKey="Avery C" first="Christy L." last="Avery">Christy L. Avery</name><affiliation wicri:level="1"><nlm:aff id="a9"><institution>Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bis, Joshua C" sort="Bis, Joshua C" uniqKey="Bis J" first="Joshua C." last="Bis">Joshua C. Bis</name><affiliation wicri:level="1"><nlm:aff id="a10"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>, Seattle, Washington 98104,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Dierckx, Bram" sort="Dierckx, Bram" uniqKey="Dierckx B" first="Bram" last="Dierckx">Bram Dierckx</name><affiliation wicri:level="1"><nlm:aff id="a11"><institution>Department of Child and Adolescent Psychiatry/Psychology, Department of Child and Adolescent Psychiatry</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a12"><institution>The Generation R Study Group, Erasmus MC</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Van Dongen, Jenny" sort="Van Dongen, Jenny" uniqKey="Van Dongen J" first="Jenny" last="Van Dongen">Jenny Van Dongen</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gogarten, Stephanie M" sort="Gogarten, Stephanie M" uniqKey="Gogarten S" first="Stephanie M." last="Gogarten">Stephanie M. Gogarten</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Goyette, Philippe" sort="Goyette, Philippe" uniqKey="Goyette P" first="Philippe" last="Goyette">Philippe Goyette</name><affiliation wicri:level="1"><nlm:aff id="a15"><institution>Montreal Heart Institute</institution>, Montreal, Quebec,<country>Canada</country> H1T 1C8</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hernesniemi, Jussi" sort="Hernesniemi, Jussi" uniqKey="Hernesniemi J" first="Jussi" last="Hernesniemi">Jussi Hernesniemi</name><affiliation wicri:level="1"><nlm:aff id="a16"><institution>Department of Clinical Chemistry, Fimlab Laboratories</institution>, Tampere 33520,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a17"><institution>Department of Clinical Chemistry, University of Tampere School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a18"><institution>Department of Cardiology, Heart Hospital, Tampere University Hospital</institution>, Tampere 33521,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Huikari, Ville" sort="Huikari, Ville" uniqKey="Huikari V" first="Ville" last="Huikari">Ville Huikari</name><affiliation wicri:level="1"><nlm:aff id="a19"><institution>Center for Life Course Health Research, University of Oulu</institution>, Oulu 90014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hwang, Shih Jen" sort="Hwang, Shih Jen" uniqKey="Hwang S" first="Shih-Jen" last="Hwang">Shih-Jen Hwang</name><affiliation wicri:level="1"><nlm:aff id="a20"><institution>Framingham Heart Study</institution>, Framingham, Massachusetts 01702,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a21"><institution>Population Sciences Branch, National Heart, Lung and Blood Institute</institution>, Bethesda, Maryland 20892,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Jaju, Deepali" sort="Jaju, Deepali" uniqKey="Jaju D" first="Deepali" last="Jaju">Deepali Jaju</name><affiliation><nlm:aff id="a22"><institution>Department of Clinical Physiology, Sultan Qaboos University Hospital</institution>, Muscat—Al Khoudh 123,<country>Sultanate of Oman</country></nlm:aff><wicri:noCountry code="nlm country">Sultanate of Oman</wicri:noCountry></affiliation></author><author><name sortKey="Kerr, Kathleen F" sort="Kerr, Kathleen F" uniqKey="Kerr K" first="Kathleen F." last="Kerr">Kathleen F. Kerr</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kluttig, Alexander" sort="Kluttig, Alexander" uniqKey="Kluttig A" first="Alexander" last="Kluttig">Alexander Kluttig</name><affiliation wicri:level="1"><nlm:aff id="a23"><institution>Institute of Medical Epidemiology, Biostatistics and Informatics, Martin-Luther-University Halle-Wittenberg</institution>, Halle (Saale) 06097,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Krijthe, Bouwe P" sort="Krijthe, Bouwe P" uniqKey="Krijthe B" first="Bouwe P." last="Krijthe">Bouwe P. Krijthe</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kumar, Jitender" sort="Kumar, Jitender" uniqKey="Kumar J" first="Jitender" last="Kumar">Jitender Kumar</name><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Department of Medical Sciences, Molecular Epidemiology, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a8"><institution>Science for Life Laboratory, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Laan, Sander W" sort="Van Der Laan, Sander W" uniqKey="Van Der Laan S" first="Sander W." last="Van Der Laan">Sander W. Van Der Laan</name><affiliation wicri:level="1"><nlm:aff id="a25"><institution>Laboratory of Experimental Cardiology, Department of Heart and Lung, University Medical Center Utrecht</institution>, Heidelberglaan 100, Utrecht 3584 CX,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lyytik Inen, Leo Pekka" sort="Lyytik Inen, Leo Pekka" uniqKey="Lyytik Inen L" first="Leo-Pekka" last="Lyytik Inen">Leo-Pekka Lyytik Inen</name><affiliation wicri:level="1"><nlm:aff id="a16"><institution>Department of Clinical Chemistry, Fimlab Laboratories</institution>, Tampere 33520,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a17"><institution>Department of Clinical Chemistry, University of Tampere School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Maihofer, Adam X" sort="Maihofer, Adam X" uniqKey="Maihofer A" first="Adam X." last="Maihofer">Adam X. Maihofer</name><affiliation wicri:level="1"><nlm:aff id="a26"><institution>Department of Psychiatry, University of California, San Diego</institution>, San Diego, California 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a27"><institution>Center for Stress and Mental Health (CESAMH), VA San Diego Healthcare System</institution>, San Diego, California 92161,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Minassian, Arpi" sort="Minassian, Arpi" uniqKey="Minassian A" first="Arpi" last="Minassian">Arpi Minassian</name><affiliation wicri:level="1"><nlm:aff id="a26"><institution>Department of Psychiatry, University of California, San Diego</institution>, San Diego, California 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a27"><institution>Center for Stress and Mental Health (CESAMH), VA San Diego Healthcare System</institution>, San Diego, California 92161,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Most, Peter J" sort="Van Der Most, Peter J" uniqKey="Van Der Most P" first="Peter J." last="Van Der Most">Peter J. Van Der Most</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Epidemiology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><affiliation wicri:level="1"><nlm:aff id="a28"><institution>Institute of Genetic Epidemiology, Helmholtz Zentrum München—German Research Center for Environmental Health</institution>, Neuherberg 85764,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a29"><institution>Department of Medicine, University Hospital Munich, Ludwig-Maximilians-University</institution>, Munich 80539,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a30"><institution>DZHK (German Centre for Cardiovascular Research), Partner site Munich Heart Alliance</institution>, Munich 80336,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nivard, Michel" sort="Nivard, Michel" uniqKey="Nivard M" first="Michel" last="Nivard">Michel Nivard</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a31"><institution>EMGO+ Institute for Health and Care Research, VU University & VU University Medical Center</institution>, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Salvi, Erika" sort="Salvi, Erika" uniqKey="Salvi E" first="Erika" last="Salvi">Erika Salvi</name><affiliation wicri:level="1"><nlm:aff id="a32"><institution>Department of Health Sciences, University of Milano</institution>, Milano 20122,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Stewart, James D" sort="Stewart, James D" uniqKey="Stewart J" first="James D." last="Stewart">James D. Stewart</name><affiliation wicri:level="1"><nlm:aff id="a9"><institution>Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a33"><institution>Carolina Population Center, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Thayer, Julian F" sort="Thayer, Julian F" uniqKey="Thayer J" first="Julian F." last="Thayer">Julian F. Thayer</name><affiliation wicri:level="1"><nlm:aff id="a34"><institution>Department of Psychology, The Ohio State University</institution>, 1835 Neil Avenue, Columbus, Ohio 43210,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Verweij, Niek" sort="Verweij, Niek" uniqKey="Verweij N" first="Niek" last="Verweij">Niek Verweij</name><affiliation wicri:level="1"><nlm:aff id="a35"><institution>Department of Cardiology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Wong, Andrew" sort="Wong, Andrew" uniqKey="Wong A" first="Andrew" last="Wong">Andrew Wong</name><affiliation wicri:level="1"><nlm:aff id="a36"><institution>MRC Unit for Lifelong Health and Ageing, University College London</institution>, 33 Bedford Place, London WC1B 5JU,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zabaneh, Delilah" sort="Zabaneh, Delilah" uniqKey="Zabaneh D" first="Delilah" last="Zabaneh">Delilah Zabaneh</name><affiliation wicri:level="1"><nlm:aff id="a37"><institution>Institute of Psychiatry, Psychology & Neuroscience, King's College London</institution>, De Crespigny Park, London SE5 8AF,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a38"><institution>University College London Genetics Institute, University College London</institution>, London WC1E 6BT,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zafarmand, Mohammad H" sort="Zafarmand, Mohammad H" uniqKey="Zafarmand M" first="Mohammad H." last="Zafarmand">Mohammad H. Zafarmand</name><affiliation wicri:level="1"><nlm:aff id="a39"><institution>Department of Public Health, Academic Medical Center (AMC), University of Amsterdam</institution>, Amsterdam 1105 AZ,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a40"><institution>Department of Obstetrics and Gynaecology, Academic Medical Centre, University of Amsterdam</institution>, Amsterdam 1105 AZ,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Abdellaoui, Abdel" sort="Abdellaoui, Abdel" uniqKey="Abdellaoui A" first="Abdel" last="Abdellaoui">Abdel Abdellaoui</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a31"><institution>EMGO+ Institute for Health and Care Research, VU University & VU University Medical Center</institution>, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Albarwani, Sulayma" sort="Albarwani, Sulayma" uniqKey="Albarwani S" first="Sulayma" last="Albarwani">Sulayma Albarwani</name><affiliation><nlm:aff id="a41"><institution>Department of Physiology, College of Medicine and Health Sciences, Sultan Qaboos University</institution>, Muscat Al-Khoudh 123,<country>Sultanate of Oman</country></nlm:aff><wicri:noCountry code="nlm country">Sultanate of Oman</wicri:noCountry></affiliation></author><author><name sortKey="Albert, Christine" sort="Albert, Christine" uniqKey="Albert C" first="Christine" last="Albert">Christine Albert</name><affiliation wicri:level="1"><nlm:aff id="a42"><institution>Brigham and Women's Hospital, Harvard Medical School</institution>, Boston, Massachusetts 02115,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Alonso, Alvaro" sort="Alonso, Alvaro" uniqKey="Alonso A" first="Alvaro" last="Alonso">Alvaro Alonso</name><affiliation wicri:level="1"><nlm:aff id="a43"><institution>Department of Epidemiology, Rollins School of Public Health, Emory University</institution>, Atlanta, Georgia 30322,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ashar, Foram" sort="Ashar, Foram" uniqKey="Ashar F" first="Foram" last="Ashar">Foram Ashar</name><affiliation wicri:level="1"><nlm:aff id="a44"><institution>McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine</institution>, Baltimore, Maryland 21205,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Auvinen, Juha" sort="Auvinen, Juha" uniqKey="Auvinen J" first="Juha" last="Auvinen">Juha Auvinen</name><affiliation wicri:level="1"><nlm:aff id="a19"><institution>Center for Life Course Health Research, University of Oulu</institution>, Oulu 90014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a45"><institution>Unit of Primary Health Care, Oulu University Hospital</institution>, Oulu 90220,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Axelsson, Tomas" sort="Axelsson, Tomas" uniqKey="Axelsson T" first="Tomas" last="Axelsson">Tomas Axelsson</name><affiliation wicri:level="1"><nlm:aff id="a46"><institution>Department of Medical Sciences, Molecular Medicine, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Baker, Dewleen G" sort="Baker, Dewleen G" uniqKey="Baker D" first="Dewleen G." last="Baker">Dewleen G. Baker</name><affiliation wicri:level="1"><nlm:aff id="a27"><institution>Center for Stress and Mental Health (CESAMH), VA San Diego Healthcare System</institution>, San Diego, California 92161,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a26"><institution>Department of Psychiatry, University of California, San Diego</institution>, San Diego, California 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Bakker, Paul I W" sort="De Bakker, Paul I W" uniqKey="De Bakker P" first="Paul I. W." last="De Bakker">Paul I. W. De Bakker</name><affiliation wicri:level="1"><nlm:aff id="a47"><institution>Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht</institution>, Utrecht 3584 CX,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a48"><institution>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht</institution>, Utrecht,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Barcella, Matteo" sort="Barcella, Matteo" uniqKey="Barcella M" first="Matteo" last="Barcella">Matteo Barcella</name><affiliation wicri:level="1"><nlm:aff id="a32"><institution>Department of Health Sciences, University of Milano</institution>, Milano 20122,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bayoumi, Riad" sort="Bayoumi, Riad" uniqKey="Bayoumi R" first="Riad" last="Bayoumi">Riad Bayoumi</name><affiliation wicri:level="1"><nlm:aff id="a49"><institution>College of Medicine, Mohammed Bin Rashid University</institution>, PO Box 505055, Dubai Healthcare City,<country>United Arab Emirates</country></nlm:aff><country xml:lang="fr">Émirats arabes unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Bieringa, Rob J" sort="Bieringa, Rob J" uniqKey="Bieringa R" first="Rob J." last="Bieringa">Rob J. Bieringa</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Epidemiology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Boomsma, Dorret" sort="Boomsma, Dorret" uniqKey="Boomsma D" first="Dorret" last="Boomsma">Dorret Boomsma</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a31"><institution>EMGO+ Institute for Health and Care Research, VU University & VU University Medical Center</institution>, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Boucher, Gabrielle" sort="Boucher, Gabrielle" uniqKey="Boucher G" first="Gabrielle" last="Boucher">Gabrielle Boucher</name><affiliation wicri:level="1"><nlm:aff id="a15"><institution>Montreal Heart Institute</institution>, Montreal, Quebec,<country>Canada</country> H1T 1C8</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Britton, Annie R" sort="Britton, Annie R" uniqKey="Britton A" first="Annie R." last="Britton">Annie R. Britton</name><affiliation wicri:level="1"><nlm:aff id="a50"><institution>Department of Epidemiology and Public Health, University College London</institution>, London WC1E 6BT,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Christophersen, Ingrid" sort="Christophersen, Ingrid" uniqKey="Christophersen I" first="Ingrid" last="Christophersen">Ingrid Christophersen</name><affiliation wicri:level="1"><nlm:aff id="a51"><institution>Cardiovascular Research Center, Massachusetts General Hospital</institution>, Boston, Massachusetts 02114,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a52"><institution>Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT</institution>, Cambridge, Massachusetts 02114,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a53"><institution>Department of Medical Research, Bærum Hospital, Vestre Viken Hospital Trust</institution>, Rud 1346,<country>Norway</country></nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Dietrich, Andrea" sort="Dietrich, Andrea" uniqKey="Dietrich A" first="Andrea" last="Dietrich">Andrea Dietrich</name><affiliation wicri:level="1"><nlm:aff id="a54"><institution>Department of Child- and Adolescent Psychiatry, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ehret, George B" sort="Ehret, George B" uniqKey="Ehret G" first="George B." last="Ehret">George B. Ehret</name><affiliation wicri:level="1"><nlm:aff id="a55"><institution>Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine</institution>, Baltimore, Maryland 21205,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a56"><institution>Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospital</institution>, Geneva 1211,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ellinor, Patrick T" sort="Ellinor, Patrick T" uniqKey="Ellinor P" first="Patrick T." last="Ellinor">Patrick T. Ellinor</name><affiliation wicri:level="1"><nlm:aff id="a52"><institution>Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT</institution>, Cambridge, Massachusetts 02114,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a57"><institution>Cardiac Arrhythmia Service & Cardiovascular Research Center, Massachusetts General Hospital</institution>, Boston, Massachusetts 02114,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Eskola, Markku" sort="Eskola, Markku" uniqKey="Eskola M" first="Markku" last="Eskola">Markku Eskola</name><affiliation wicri:level="1"><nlm:aff id="a18"><institution>Department of Cardiology, Heart Hospital, Tampere University Hospital</institution>, Tampere 33521,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a58"><institution>Department of Cardiology, University of Tampere School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Felix, Janine F" sort="Felix, Janine F" uniqKey="Felix J" first="Janine F." last="Felix">Janine F. Felix</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Floras, John S" sort="Floras, John S" uniqKey="Floras J" first="John S." last="Floras">John S. Floras</name><affiliation wicri:level="1"><nlm:aff id="a59"><institution>University Health Network and Mount Sinai Hospital Division of Cardiology, Department of Medicine, University of Toronto</institution>, Ontario,<country>Canada</country> M5S</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a60"><institution>Toronto General Research Institute, University Health Network</institution>, Toronto,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H." last="Franco">Oscar H. Franco</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Friberg, Peter" sort="Friberg, Peter" uniqKey="Friberg P" first="Peter" last="Friberg">Peter Friberg</name><affiliation wicri:level="1"><nlm:aff id="a61"><institution>Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska University Hospital, University of Gothenburg</institution>, Gothenburg,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gademan, Maaike G J" sort="Gademan, Maaike G J" uniqKey="Gademan M" first="Maaike G. J." last="Gademan">Maaike G. J. Gademan</name><affiliation wicri:level="1"><nlm:aff id="a39"><institution>Department of Public Health, Academic Medical Center (AMC), University of Amsterdam</institution>, Amsterdam 1105 AZ,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Geyer, Mark A" sort="Geyer, Mark A" uniqKey="Geyer M" first="Mark A." last="Geyer">Mark A. Geyer</name><affiliation wicri:level="1"><nlm:aff id="a26"><institution>Department of Psychiatry, University of California, San Diego</institution>, San Diego, California 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Giedraitis, Vilmantas" sort="Giedraitis, Vilmantas" uniqKey="Giedraitis V" first="Vilmantas" last="Giedraitis">Vilmantas Giedraitis</name><affiliation wicri:level="1"><nlm:aff id="a62"><institution>Department of Public Health and Caring Sciences, Molecular Geriatrics, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hartman, Catharina A" sort="Hartman, Catharina A" uniqKey="Hartman C" first="Catharina A." last="Hartman">Catharina A. Hartman</name><affiliation wicri:level="1"><nlm:aff id="a63"><institution>Interdisciplinary Center Psychopathology and Emotion regulation, Department of Psychiatry, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hemerich, Daiane" sort="Hemerich, Daiane" uniqKey="Hemerich D" first="Daiane" last="Hemerich">Daiane Hemerich</name><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht</institution>, Heidelberglaan 100, Utrecht 3584CX,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a64"><institution>CAPES Foundation, Ministry of Education of Brazil</institution>, Brasília DF 70040-020,<country>Brazil</country></nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a31"><institution>EMGO+ Institute for Health and Care Research, VU University & VU University Medical Center</institution>, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Huikuri, Heikki" sort="Huikuri, Heikki" uniqKey="Huikuri H" first="Heikki" last="Huikuri">Heikki Huikuri</name><affiliation wicri:level="1"><nlm:aff id="a65"><institution>Research Unit of Internal Medicine, Medical Research Center Oulu, Oulu University Hospital and University of Oulu</institution>, Oulu 90220,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hutri K Honen, Nina" sort="Hutri K Honen, Nina" uniqKey="Hutri K Honen N" first="Nina" last="Hutri-K Hönen">Nina Hutri-K Hönen</name><affiliation wicri:level="1"><nlm:aff id="a66"><institution>Department of Pediatrics, Tampere University Hospital</institution>, Tampere 33521,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a67"><institution>Department of Pediatrics, University of Tampere School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Jouven, Xavier" sort="Jouven, Xavier" uniqKey="Jouven X" first="Xavier" last="Jouven">Xavier Jouven</name><affiliation wicri:level="1"><nlm:aff id="a68"><institution>INSERM U970, Paris Descartes University</institution>, Paris 75006,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Junttila, Juhani" sort="Junttila, Juhani" uniqKey="Junttila J" first="Juhani" last="Junttila">Juhani Junttila</name><affiliation wicri:level="1"><nlm:aff id="a65"><institution>Research Unit of Internal Medicine, Medical Research Center Oulu, Oulu University Hospital and University of Oulu</institution>, Oulu 90220,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Juonala, Markus" sort="Juonala, Markus" uniqKey="Juonala M" first="Markus" last="Juonala">Markus Juonala</name><affiliation wicri:level="1"><nlm:aff id="a69"><institution>Department of Medicine, University of Turku</institution>, Turku 20520,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a70"><institution>Division of Medicine, Turku University Hospital</institution>, Turku 20521,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kiviniemi, Antti M" sort="Kiviniemi, Antti M" uniqKey="Kiviniemi A" first="Antti M." last="Kiviniemi">Antti M. Kiviniemi</name><affiliation wicri:level="1"><nlm:aff id="a65"><institution>Research Unit of Internal Medicine, Medical Research Center Oulu, Oulu University Hospital and University of Oulu</institution>, Oulu 90220,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kors, Jan A" sort="Kors, Jan A" uniqKey="Kors J" first="Jan A." last="Kors">Jan A. Kors</name><affiliation wicri:level="1"><nlm:aff id="a71"><institution>Department of Medical Informatics, Erasmus Medical Center</institution>, Rotterdam 3015 CE,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name><affiliation wicri:level="1"><nlm:aff id="a50"><institution>Department of Epidemiology and Public Health, University College London</institution>, London WC1E 6BT,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a72"><institution>ISER, Essex University</institution>, Colchester, Essex CO4 3SQ,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kuznetsova, Tatiana" sort="Kuznetsova, Tatiana" uniqKey="Kuznetsova T" first="Tatiana" last="Kuznetsova">Tatiana Kuznetsova</name><affiliation wicri:level="1"><nlm:aff id="a73"><institution>Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven</institution>, Leuven 3000,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Laurie, Cathy C" sort="Laurie, Cathy C" uniqKey="Laurie C" first="Cathy C." last="Laurie">Cathy C. Laurie</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lefrandt, Joop D" sort="Lefrandt, Joop D" uniqKey="Lefrandt J" first="Joop D." last="Lefrandt">Joop D. Lefrandt</name><affiliation wicri:level="1"><nlm:aff id="a74"><institution>Department of Internal Medicine, Division of Vascular Medicine, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Li, Yong" sort="Li, Yong" uniqKey="Li Y" first="Yong" last="Li">Yong Li</name><affiliation wicri:level="1"><nlm:aff id="a75"><institution>Division of Genetic Epidemiology, Institute for Medical Biometry and Statistics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg</institution>, Freiburg 79110,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Li, Yun" sort="Li, Yun" uniqKey="Li Y" first="Yun" last="Li">Yun Li</name><affiliation wicri:level="1"><nlm:aff id="a76"><institution>Department of Genetics, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a77"><institution>Department of Biostatistics, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a78"><institution>Department of Computer Science, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Liao, Duanping" sort="Liao, Duanping" uniqKey="Liao D" first="Duanping" last="Liao">Duanping Liao</name><affiliation wicri:level="1"><nlm:aff id="a79"><institution>Division of Epidemiology, Department of Public Health Sciences, Penn State University College of Medicine</institution>, Hershey, Pennsylvania 17033,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Limacher, Marian C" sort="Limacher, Marian C" uniqKey="Limacher M" first="Marian C." last="Limacher">Marian C. Limacher</name><affiliation wicri:level="1"><nlm:aff id="a80"><institution>Division of Cardiovascular Medicine, University of Florida College of Medicine</institution>, Gainesville, Florida 32611,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lin, Henry J" sort="Lin, Henry J" uniqKey="Lin H" first="Henry J." last="Lin">Henry J. Lin</name><affiliation wicri:level="1"><nlm:aff id="a81"><institution>Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center</institution>, Torrance, California 90502,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a82"><institution>Division of Medical Genetics, Department of Pediatrics, Harbor-UCLA Medical Center</institution>, Torrance, California 90502,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lindgren, Cecilia M" sort="Lindgren, Cecilia M" uniqKey="Lindgren C" first="Cecilia M." last="Lindgren">Cecilia M. Lindgren</name><affiliation wicri:level="1"><nlm:aff id="a83"><institution>Li Ka Shing Centre for Health Information and Discovery, The Big Data Institute, University of Oxford</institution>, Oxford OX3 7BN,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a84"><institution>Wellcome Trust Centre for Human Genetics, University of Oxford</institution>, Oxford OX3 7BN,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lubitz, Steven A" sort="Lubitz, Steven A" uniqKey="Lubitz S" first="Steven A." last="Lubitz">Steven A. Lubitz</name><affiliation wicri:level="1"><nlm:aff id="a52"><institution>Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT</institution>, Cambridge, Massachusetts 02114,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a57"><institution>Cardiac Arrhythmia Service & Cardiovascular Research Center, Massachusetts General Hospital</institution>, Boston, Massachusetts 02114,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mahajan, Anubha" sort="Mahajan, Anubha" uniqKey="Mahajan A" first="Anubha" last="Mahajan">Anubha Mahajan</name><affiliation wicri:level="1"><nlm:aff id="a84"><institution>Wellcome Trust Centre for Human Genetics, University of Oxford</institution>, Oxford OX3 7BN,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mcknight, Barbara" sort="Mcknight, Barbara" uniqKey="Mcknight B" first="Barbara" last="Mcknight">Barbara Mcknight</name><affiliation wicri:level="1"><nlm:aff id="a10"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>, Seattle, Washington 98104,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a85"><institution>Public Health Sciences Division, Fred Hutchinson Cancer Research Center</institution>, Seattle, Washington 98109,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zu Schwabedissen, Henriette Meyer" sort="Zu Schwabedissen, Henriette Meyer" uniqKey="Zu Schwabedissen H" first="Henriette Meyer" last="Zu Schwabedissen">Henriette Meyer Zu Schwabedissen</name><affiliation wicri:level="1"><nlm:aff id="a86"><institution>Biopharmacy, Department Pharmaceutical Sciences, University of Basel</institution>, Basel CH-4056,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Milaneschi, Yuri" sort="Milaneschi, Yuri" uniqKey="Milaneschi Y" first="Yuri" last="Milaneschi">Yuri Milaneschi</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Department of Psychiatry, EMGO Institute for Health and Care Research and Neuroscience Campus Amsterdam, VU University Medical Center/GGZ inGeest</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mononen, Nina" sort="Mononen, Nina" uniqKey="Mononen N" first="Nina" last="Mononen">Nina Mononen</name><affiliation wicri:level="1"><nlm:aff id="a16"><institution>Department of Clinical Chemistry, Fimlab Laboratories</institution>, Tampere 33520,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a17"><institution>Department of Clinical Chemistry, University of Tampere School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Morris, Andrew P" sort="Morris, Andrew P" uniqKey="Morris A" first="Andrew P." last="Morris">Andrew P. Morris</name><affiliation wicri:level="1"><nlm:aff id="a84"><institution>Wellcome Trust Centre for Human Genetics, University of Oxford</institution>, Oxford OX3 7BN,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a87"><institution>Department of Biostatistics, University of Liverpool</institution>, Liverpool L69 3GL,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nalls, Mike A" sort="Nalls, Mike A" uniqKey="Nalls M" first="Mike A." last="Nalls">Mike A. Nalls</name><affiliation wicri:level="1"><nlm:aff id="a88"><institution>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health</institution>, Bethesda, Maryland 20892,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Navis, Gerjan" sort="Navis, Gerjan" uniqKey="Navis G" first="Gerjan" last="Navis">Gerjan Navis</name><affiliation wicri:level="1"><nlm:aff id="a89"><institution>Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Neijts, Melanie" sort="Neijts, Melanie" uniqKey="Neijts M" first="Melanie" last="Neijts">Melanie Neijts</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a31"><institution>EMGO+ Institute for Health and Care Research, VU University & VU University Medical Center</institution>, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nikus, Kjell" sort="Nikus, Kjell" uniqKey="Nikus K" first="Kjell" last="Nikus">Kjell Nikus</name><affiliation wicri:level="1"><nlm:aff id="a18"><institution>Department of Cardiology, Heart Hospital, Tampere University Hospital</institution>, Tampere 33521,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a90"><institution>Department of Cardiology, University of Tampere, School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="North, Kari E" sort="North, Kari E" uniqKey="North K" first="Kari E." last="North">Kari E. North</name><affiliation wicri:level="1"><nlm:aff id="a9"><institution>Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a91"><institution>Carolina Center for Genome Sciences, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="O Connor, Daniel T" sort="O Connor, Daniel T" uniqKey="O Connor D" first="Daniel T." last="O'Connor">Daniel T. O'Connor</name><affiliation wicri:level="1"><nlm:aff id="a92"><institution>Department of Medicine, University of California, San Diego</institution>, San Diego, California 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ormel, Johan" sort="Ormel, Johan" uniqKey="Ormel J" first="Johan" last="Ormel">Johan Ormel</name><affiliation wicri:level="1"><nlm:aff id="a63"><institution>Interdisciplinary Center Psychopathology and Emotion regulation, Department of Psychiatry, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Perz, Siegfried" sort="Perz, Siegfried" uniqKey="Perz S" first="Siegfried" last="Perz">Siegfried Perz</name><affiliation wicri:level="1"><nlm:aff id="a93"><institution>Institute of Epidemiology II, Helmholtz Zentrum München—German Research Center for Environmental Health</institution>, Neuherberg 85764,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name><affiliation wicri:level="1"><nlm:aff id="a30"><institution>DZHK (German Centre for Cardiovascular Research), Partner site Munich Heart Alliance</institution>, Munich 80336,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a93"><institution>Institute of Epidemiology II, Helmholtz Zentrum München—German Research Center for Environmental Health</institution>, Neuherberg 85764,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a94"><institution>German Center for Diabetes Research</institution>, Neuherberg 85764,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M." last="Psaty">Bruce M. Psaty</name><affiliation wicri:level="1"><nlm:aff id="a10"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>, Seattle, Washington 98104,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a95"><institution>Departments of Epidemiology and Health Services, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a96"><institution>Group Health Research Institute, Group Health Cooperative</institution>, Seattle, Washington 98101,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Raitakari, Olli T" sort="Raitakari, Olli T" uniqKey="Raitakari O" first="Olli T." last="Raitakari">Olli T. Raitakari</name><affiliation wicri:level="1"><nlm:aff id="a97"><institution>Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital</institution>, Turku 20521,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a98"><institution>Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku</institution>, Turku 20520,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Risbrough, Victoria B" sort="Risbrough, Victoria B" uniqKey="Risbrough V" first="Victoria B." last="Risbrough">Victoria B. Risbrough</name><affiliation wicri:level="1"><nlm:aff id="a26"><institution>Department of Psychiatry, University of California, San Diego</institution>, San Diego, California 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a27"><institution>Center for Stress and Mental Health (CESAMH), VA San Diego Healthcare System</institution>, San Diego, California 92161,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sinner, Moritz F" sort="Sinner, Moritz F" uniqKey="Sinner M" first="Moritz F." last="Sinner">Moritz F. Sinner</name><affiliation wicri:level="1"><nlm:aff id="a29"><institution>Department of Medicine, University Hospital Munich, Ludwig-Maximilians-University</institution>, Munich 80539,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a30"><institution>DZHK (German Centre for Cardiovascular Research), Partner site Munich Heart Alliance</institution>, Munich 80336,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Siscovick, David" sort="Siscovick, David" uniqKey="Siscovick D" first="David" last="Siscovick">David Siscovick</name><affiliation wicri:level="1"><nlm:aff id="a99"><institution>The New York Academy of Medicine</institution>, New York, New York 10029,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Smit, Johannes H" sort="Smit, Johannes H" uniqKey="Smit J" first="Johannes H." last="Smit">Johannes H. Smit</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Department of Psychiatry, EMGO Institute for Health and Care Research and Neuroscience Campus Amsterdam, VU University Medical Center/GGZ inGeest</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Smith, Nicholas L" sort="Smith, Nicholas L" uniqKey="Smith N" first="Nicholas L." last="Smith">Nicholas L. Smith</name><affiliation wicri:level="1"><nlm:aff id="a96"><institution>Group Health Research Institute, Group Health Cooperative</institution>, Seattle, Washington 98101,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a100"><institution>Department of Epidemiology, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a101"><institution>Seattle Epidemiologic Research and Information Center, Veterans Affairs Office of Research and Development</institution>, Seattle, Washington 98108,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Soliman, Elsayed Z" sort="Soliman, Elsayed Z" uniqKey="Soliman E" first="Elsayed Z." last="Soliman">Elsayed Z. Soliman</name><affiliation wicri:level="1"><nlm:aff id="a102"><institution>Epidemiological Cardiology Research Center (EPICARE), Division of Public Health Sciences, Wake Forest School of Medicine</institution>, Winston-Salem, North Carolina 27157,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sotoodehnia, Nona" sort="Sotoodehnia, Nona" uniqKey="Sotoodehnia N" first="Nona" last="Sotoodehnia">Nona Sotoodehnia</name><affiliation wicri:level="1"><nlm:aff id="a103"><institution>Cardiovascular Health Research Unit, Division of Cardiology, Departments of Medicine and Epidemiology, University of Washington</institution>, Seattle, Washington 98101,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Staessen, Jan A" sort="Staessen, Jan A" uniqKey="Staessen J" first="Jan A." last="Staessen">Jan A. Staessen</name><affiliation wicri:level="1"><nlm:aff id="a73"><institution>Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven</institution>, Leuven 3000,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Stein, Phyllis K" sort="Stein, Phyllis K" uniqKey="Stein P" first="Phyllis K." last="Stein">Phyllis K. Stein</name><affiliation wicri:level="1"><nlm:aff id="a104"><institution>Heart Rate Variability Lab, Washington University School of Medicine</institution>, St Louis, Missouri 63108,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Stilp, Adrienne M" sort="Stilp, Adrienne M" uniqKey="Stilp A" first="Adrienne M." last="Stilp">Adrienne M. Stilp</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Stolarz Skrzypek, Katarzyna" sort="Stolarz Skrzypek, Katarzyna" uniqKey="Stolarz Skrzypek K" first="Katarzyna" last="Stolarz-Skrzypek">Katarzyna Stolarz-Skrzypek</name><affiliation wicri:level="1"><nlm:aff id="a105"><institution>First Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College</institution>, Cracow 31-008,<country>Poland</country></nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name><affiliation wicri:level="1"><nlm:aff id="a28"><institution>Institute of Genetic Epidemiology, Helmholtz Zentrum München—German Research Center for Environmental Health</institution>, Neuherberg 85764,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a106"><institution>Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität</institution>, Munich 81377,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sundstrom, Johan" sort="Sundstrom, Johan" uniqKey="Sundstrom J" first="Johan" last="Sundström">Johan Sundström</name><affiliation wicri:level="1"><nlm:aff id="a107"><institution>Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University</institution>, Uppsala 751 85,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Swenne, Cees A" sort="Swenne, Cees A" uniqKey="Swenne C" first="Cees A." last="Swenne">Cees A. Swenne</name><affiliation wicri:level="1"><nlm:aff id="a108"><institution>Department of Cardiology, Leiden University Medical Center</institution>, Leiden 2300 RC,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Syv Nen, Ann Christine" sort="Syv Nen, Ann Christine" uniqKey="Syv Nen A" first="Ann-Christine" last="Syv Nen">Ann-Christine Syv Nen</name><affiliation wicri:level="1"><nlm:aff id="a46"><institution>Department of Medical Sciences, Molecular Medicine, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tardif, Jean Claude" sort="Tardif, Jean Claude" uniqKey="Tardif J" first="Jean-Claude" last="Tardif">Jean-Claude Tardif</name><affiliation wicri:level="1"><nlm:aff id="a15"><institution>Montreal Heart Institute</institution>, Montreal, Quebec,<country>Canada</country> H1T 1C8</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a109"><institution>Université de Montréal</institution>, Montreal, Quebec,<country>Canada</country> H3T IJ4</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Taylor, Kent D" sort="Taylor, Kent D" uniqKey="Taylor K" first="Kent D." last="Taylor">Kent D. Taylor</name><affiliation wicri:level="1"><nlm:aff id="a110"><institution>Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center</institution>, Torrance, California 90509,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><affiliation wicri:level="1"><nlm:aff id="a111"><institution>Institute for Community Medicine, University Medicine Greifswald</institution>, Greifswald 17475,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Thornton, Timothy A" sort="Thornton, Timothy A" uniqKey="Thornton T" first="Timothy A." last="Thornton">Timothy A. Thornton</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tinker, Lesley E" sort="Tinker, Lesley E" uniqKey="Tinker L" first="Lesley E." last="Tinker">Lesley E. Tinker</name><affiliation wicri:level="1"><nlm:aff id="a85"><institution>Public Health Sciences Division, Fred Hutchinson Cancer Research Center</institution>, Seattle, Washington 98109,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G." last="Uitterlinden">André G. Uitterlinden</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a112"><institution>Department of Internal Medicine, Erasmus University Medical Center</institution>, Rotterdam 3015 CE,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a113"><institution>Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging NCHA)</institution>, Leiden 2300 RC,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Van Setten, Jessica" sort="Van Setten, Jessica" uniqKey="Van Setten J" first="Jessica" last="Van Setten">Jessica Van Setten</name><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht</institution>, Heidelberglaan 100, Utrecht 3584CX,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Voss, Andreas" sort="Voss, Andreas" uniqKey="Voss A" first="Andreas" last="Voss">Andreas Voss</name><affiliation wicri:level="1"><nlm:aff id="a114"><institution>Institute of Innovative Health Technologies—IGHT Jena Ernst-Abbe-Hochschule Jena</institution>, Jena 07745,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Waldenberger, Melanie" sort="Waldenberger, Melanie" uniqKey="Waldenberger M" first="Melanie" last="Waldenberger">Melanie Waldenberger</name><affiliation wicri:level="1"><nlm:aff id="a93"><institution>Institute of Epidemiology II, Helmholtz Zentrum München—German Research Center for Environmental Health</institution>, Neuherberg 85764,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a115"><institution>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München—German Research Center for Environmental Health</institution>, Neuherberg 85764,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Wilhelmsen, Kirk C" sort="Wilhelmsen, Kirk C" uniqKey="Wilhelmsen K" first="Kirk C." last="Wilhelmsen">Kirk C. Wilhelmsen</name><affiliation wicri:level="1"><nlm:aff id="a116"><institution>Departments of Genetics and Neurology University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a117"><institution>The Renaissance Computing Institute</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a31"><institution>EMGO+ Institute for Health and Care Research, VU University & VU University Medical Center</institution>, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Wong, Quenna" sort="Wong, Quenna" uniqKey="Wong Q" first="Quenna" last="Wong">Quenna Wong</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Zhu Ming" sort="Zhang, Zhu Ming" uniqKey="Zhang Z" first="Zhu-Ming" last="Zhang">Zhu-Ming Zhang</name><affiliation wicri:level="1"><nlm:aff id="a102"><institution>Epidemiological Cardiology Research Center (EPICARE), Division of Public Health Sciences, Wake Forest School of Medicine</institution>, Winston-Salem, North Carolina 27157,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a118"><institution>Department of Epidemiology & Prevention, Division of Public Health Sciences, Wake Forest School of Medicine</institution>, Winston-Salem, North Carolina 27157,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zonderman, Alan B" sort="Zonderman, Alan B" uniqKey="Zonderman A" first="Alan B." last="Zonderman">Alan B. Zonderman</name><affiliation wicri:level="1"><nlm:aff id="a119"><institution>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health</institution>, Baltimore, Maryland 21224,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Cusi, Daniele" sort="Cusi, Daniele" uniqKey="Cusi D" first="Daniele" last="Cusi">Daniele Cusi</name><affiliation wicri:level="1"><nlm:aff id="a120"><institution>Institute of Biomedical Technologies, CNR—Italian National Research Council</institution>, Milan 20090,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a121"><institution>KOS Genetic SRL</institution>, Bresso (Milano) 20091,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Evans, Michele K" sort="Evans, Michele K" uniqKey="Evans M" first="Michele K." last="Evans">Michele K. Evans</name><affiliation wicri:level="1"><nlm:aff id="a119"><institution>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health</institution>, Baltimore, Maryland 21224,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Greiser, Halina K" sort="Greiser, Halina K" uniqKey="Greiser H" first="Halina K." last="Greiser">Halina K. Greiser</name><affiliation wicri:level="1"><nlm:aff id="a122"><institution>German Cancer Research Centre, Division of Cancer Epidemiology</institution>, Heidelberg 69210,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Van Der Harst, Pim" sort="Van Der Harst, Pim" uniqKey="Van Der Harst P" first="Pim" last="Van Der Harst">Pim Van Der Harst</name><affiliation wicri:level="1"><nlm:aff id="a35"><institution>Department of Cardiology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hassan, Mohammad" sort="Hassan, Mohammad" uniqKey="Hassan M" first="Mohammad" last="Hassan">Mohammad Hassan</name><affiliation><nlm:aff id="a41"><institution>Department of Physiology, College of Medicine and Health Sciences, Sultan Qaboos University</institution>, Muscat Al-Khoudh 123,<country>Sultanate of Oman</country></nlm:aff><wicri:noCountry code="nlm country">Sultanate of Oman</wicri:noCountry></affiliation></author><author><name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Department of Medical Sciences, Molecular Epidemiology, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a8"><institution>Science for Life Laboratory, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a123"><institution>Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine</institution>, Stanford, California 94305,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name><affiliation wicri:level="1"><nlm:aff id="a19"><institution>Center for Life Course Health Research, University of Oulu</institution>, Oulu 90014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a45"><institution>Unit of Primary Health Care, Oulu University Hospital</institution>, Oulu 90220,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a124"><institution>Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, St Mary’s campus, Imperial College London</institution>, London W2 1PG,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a125"><institution>Biocenter Oulu University of Oulu</institution>, Oulu 90014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="K B, Stefan" sort="K B, Stefan" uniqKey="K B S" first="Stefan" last="K B">Stefan K B</name><affiliation wicri:level="1"><nlm:aff id="a29"><institution>Department of Medicine, University Hospital Munich, Ludwig-Maximilians-University</institution>, Munich 80539,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a30"><institution>DZHK (German Centre for Cardiovascular Research), Partner site Munich Heart Alliance</institution>, Munich 80336,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="K Honen, Mika" sort="K Honen, Mika" uniqKey="K Honen M" first="Mika" last="K Hönen">Mika K Hönen</name><affiliation wicri:level="1"><nlm:aff id="a126"><institution>Department of Clinical Physiology, Tampere University Hospital</institution>, Tampere 33521,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a127"><institution>Department of Clinical Physiology, University of Tampere, School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kivimaki, Mika" sort="Kivimaki, Mika" uniqKey="Kivimaki M" first="Mika" last="Kivimaki">Mika Kivimaki</name><affiliation wicri:level="1"><nlm:aff id="a50"><institution>Department of Epidemiology and Public Health, University College London</institution>, London WC1E 6BT,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kooperberg, Charles" sort="Kooperberg, Charles" uniqKey="Kooperberg C" first="Charles" last="Kooperberg">Charles Kooperberg</name><affiliation wicri:level="1"><nlm:aff id="a85"><institution>Public Health Sciences Division, Fred Hutchinson Cancer Research Center</institution>, Seattle, Washington 98109,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kuh, Diana" sort="Kuh, Diana" uniqKey="Kuh D" first="Diana" last="Kuh">Diana Kuh</name><affiliation wicri:level="1"><nlm:aff id="a36"><institution>MRC Unit for Lifelong Health and Ageing, University College London</institution>, 33 Bedford Place, London WC1B 5JU,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name><affiliation wicri:level="1"><nlm:aff id="a16"><institution>Department of Clinical Chemistry, Fimlab Laboratories</institution>, Tampere 33520,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a17"><institution>Department of Clinical Chemistry, University of Tampere School of Medicine</institution>, Tampere 33014,<country>Finland</country></nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name><affiliation wicri:level="1"><nlm:aff id="a107"><institution>Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University</institution>, Uppsala 751 85,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nievergelt, Caroline M" sort="Nievergelt, Caroline M" uniqKey="Nievergelt C" first="Caroline M." last="Nievergelt">Caroline M. Nievergelt</name><affiliation wicri:level="1"><nlm:aff id="a26"><institution>Department of Psychiatry, University of California, San Diego</institution>, San Diego, California 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a27"><institution>Center for Stress and Mental Health (CESAMH), VA San Diego Healthcare System</institution>, San Diego, California 92161,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="O Donnell, Chris J" sort="O Donnell, Chris J" uniqKey="O Donnell C" first="Chris J." last="O'Donnell">Chris J. O'Donnell</name><affiliation wicri:level="1"><nlm:aff id="a20"><institution>Framingham Heart Study</institution>, Framingham, Massachusetts 01702,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a21"><institution>Population Sciences Branch, National Heart, Lung and Blood Institute</institution>, Bethesda, Maryland 20892,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a128"><institution>Cardiology Section, Boston Veteran’s Administration Healthcare</institution>, Boston, Maryland 02132,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Oldehinkel, Albertine J" sort="Oldehinkel, Albertine J" uniqKey="Oldehinkel A" first="Albertine J." last="Oldehinkel">Albertine J. Oldehinkel</name><affiliation wicri:level="1"><nlm:aff id="a63"><institution>Interdisciplinary Center Psychopathology and Emotion regulation, Department of Psychiatry, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Penninx, Brenda" sort="Penninx, Brenda" uniqKey="Penninx B" first="Brenda" last="Penninx">Brenda Penninx</name><affiliation wicri:level="1"><nlm:aff id="a5"><institution>Department of Psychiatry, EMGO Institute for Health and Care Research and Neuroscience Campus Amsterdam, VU University Medical Center/GGZ inGeest</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Reiner, Alexander P" sort="Reiner, Alexander P" uniqKey="Reiner A" first="Alexander P." last="Reiner">Alexander P. Reiner</name><affiliation wicri:level="1"><nlm:aff id="a85"><institution>Public Health Sciences Division, Fred Hutchinson Cancer Research Center</institution>, Seattle, Washington 98109,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a100"><institution>Department of Epidemiology, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Riese, Harriette" sort="Riese, Harriette" uniqKey="Riese H" first="Harriëtte" last="Riese">Harriëtte Riese</name><affiliation wicri:level="1"><nlm:aff id="a63"><institution>Interdisciplinary Center Psychopathology and Emotion regulation, Department of Psychiatry, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Van Roon, Arie M" sort="Van Roon, Arie M" uniqKey="Van Roon A" first="Arie M." last="Van Roon">Arie M. Van Roon</name><affiliation wicri:level="1"><nlm:aff id="a74"><institution>Department of Internal Medicine, Division of Vascular Medicine, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Rioux, John D" sort="Rioux, John D" uniqKey="Rioux J" first="John D." last="Rioux">John D. Rioux</name><affiliation wicri:level="1"><nlm:aff id="a15"><institution>Montreal Heart Institute</institution>, Montreal, Quebec,<country>Canada</country> H1T 1C8</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a109"><institution>Université de Montréal</institution>, Montreal, Quebec,<country>Canada</country> H3T IJ4</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I." last="Rotter">Jerome I. Rotter</name><affiliation wicri:level="1"><nlm:aff id="a110"><institution>Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center</institution>, Torrance, California 90509,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Sofer, Tamar" sort="Sofer, Tamar" uniqKey="Sofer T" first="Tamar" last="Sofer">Tamar Sofer</name><affiliation wicri:level="1"><nlm:aff id="a14"><institution>Department of Biostatistics, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Stricker, Bruno H" sort="Stricker, Bruno H" uniqKey="Stricker B" first="Bruno H." last="Stricker">Bruno H. Stricker</name><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a129"><institution>Inspectorate for Health Care</institution>, The Hague 2511 VX,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tiemeier, Henning" sort="Tiemeier, Henning" uniqKey="Tiemeier H" first="Henning" last="Tiemeier">Henning Tiemeier</name><affiliation wicri:level="1"><nlm:aff id="a11"><institution>Department of Child and Adolescent Psychiatry/Psychology, Department of Child and Adolescent Psychiatry</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a24"><institution>Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam</institution>, PO Box 2060, Rotterdam 3000 CB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Vrijkotte, Tanja G M" sort="Vrijkotte, Tanja G M" uniqKey="Vrijkotte T" first="Tanja G. M." last="Vrijkotte">Tanja G. M. Vrijkotte</name><affiliation wicri:level="1"><nlm:aff id="a39"><institution>Department of Public Health, Academic Medical Center (AMC), University of Amsterdam</institution>, Amsterdam 1105 AZ,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Asselbergs, Folkert W" sort="Asselbergs, Folkert W" uniqKey="Asselbergs F" first="Folkert W." last="Asselbergs">Folkert W. Asselbergs</name><affiliation wicri:level="1"><nlm:aff id="a2"><institution>Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht</institution>, Heidelberglaan 100, Utrecht 3584CX,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a130"><institution>Institute of Cardiovascular Science, University College London</institution>, 222 Euston Road, London NW1 2DA,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a131"><institution>Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute</institution>, Utrecht 3501 DG,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Brundel, Bianca J J M" sort="Brundel, Bianca J J M" uniqKey="Brundel B" first="Bianca J. J. M." last="Brundel">Bianca J. J. M. Brundel</name><affiliation wicri:level="1"><nlm:aff id="a132"><institution>Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center</institution>, De Boelelaan 1118, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Heckbert, Susan R" sort="Heckbert, Susan R" uniqKey="Heckbert S" first="Susan R." last="Heckbert">Susan R. Heckbert</name><affiliation wicri:level="1"><nlm:aff id="a10"><institution>Cardiovascular Health Research Unit, Department of Medicine, University of Washington</institution>, Seattle, Washington 98104,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a100"><institution>Department of Epidemiology, School of Public Health, University of Washington</institution>, Seattle, Washington 98195,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Whitsel, Eric A" sort="Whitsel, Eric A" uniqKey="Whitsel E" first="Eric A." last="Whitsel">Eric A. Whitsel</name><affiliation wicri:level="1"><nlm:aff id="a9"><institution>Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a133"><institution>Department of Medicine, University of North Carolina</institution>, Chapel Hill, North Carolina 27599,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Den Hoed, Marcel" sort="Den Hoed, Marcel" uniqKey="Den Hoed M" first="Marcel" last="Den Hoed">Marcel Den Hoed</name><affiliation wicri:level="1"><nlm:aff id="a7"><institution>Department of Medical Sciences, Molecular Epidemiology, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a8"><institution>Science for Life Laboratory, Uppsala University</institution>, Uppsala 75237,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Snieder, Harold" sort="Snieder, Harold" uniqKey="Snieder H" first="Harold" last="Snieder">Harold Snieder</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Department of Epidemiology, University of Groningen, University Medical Center Groningen</institution>, PO Box 30001, Groningen 9700 RB,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="De Geus, Eco J C" sort="De Geus, Eco J C" uniqKey="De Geus E" first="Eco J. C." last="De Geus">Eco J. C. De Geus</name><affiliation wicri:level="1"><nlm:aff id="a13"><institution>Department of Biological Psychology, Behavioral and Movement Sciences, VU University</institution>, Amsterdam 1081 BT,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="a31"><institution>EMGO+ Institute for Health and Care Research, VU University & VU University Medical Center</institution>, Amsterdam 1081 HV,<country>The Netherlands</country></nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Nature Communications</title><idno type="eISSN">2041-1723</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Reduced cardiac vagal control reflected in low heart rate variability (HRV) is associated with greater risks for cardiac morbidity and mortality. In two-stage meta-analyses of genome-wide association studies for three HRV traits in up to 53,174 individuals of European ancestry, we detect 17 genome-wide significant SNPs in eight loci. HRV SNPs tag non-synonymous SNPs (in <italic>NDUFA11</italic> and <italic>KIAA1755</italic>), expression quantitative trait loci (eQTLs) (influencing <italic>GNG11</italic>, <italic>RGS6</italic> and <italic>NEO1</italic>), or are located in genes preferentially expressed in the sinoatrial node (<italic>GNG11</italic>, <italic>RGS6</italic> and <italic>HCN4)</italic>. Genetic risk scores account for 0.9 to 2.6% of the HRV variance. Significant genetic correlation is found for HRV with heart rate (−0.74<<italic>r</italic><sub><italic>g</italic></sub><−0.55) and blood pressure (−0.35<<italic>r</italic><sub><italic>g</italic></sub><−0.20). These findings provide clinically relevant biological insight into heritable variation in vagal heart rhythm regulation, with a key role for genetic variants (<italic>GNG11</italic>, <italic>RGS6)</italic> that influence G-protein heterotrimer action in GIRK-channel induced pacemaker membrane hyperpolarization.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Berntson, G G" uniqKey="Berntson G">G. G. Berntson</name></author><author><name sortKey="Cacioppo, J T" uniqKey="Cacioppo J">J. T. Cacioppo</name></author><author><name sortKey="Quigley, K S" uniqKey="Quigley K">K. S. Quigley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eckberg, D L" uniqKey="Eckberg D">D. L. Eckberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Munoz, M L" uniqKey="Munoz M">M. L. 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Nolte</name></noRegion><name sortKey="Abdellaoui, Abdel" sort="Abdellaoui, Abdel" uniqKey="Abdellaoui A" first="Abdel" last="Abdellaoui">Abdel Abdellaoui</name><name sortKey="Abdellaoui, Abdel" sort="Abdellaoui, Abdel" uniqKey="Abdellaoui A" first="Abdel" last="Abdellaoui">Abdel Abdellaoui</name><name sortKey="Amare, Azmeraw T" sort="Amare, Azmeraw T" uniqKey="Amare A" first="Azmeraw T." last="Amare">Azmeraw T. Amare</name><name sortKey="Asselbergs, Folkert W" sort="Asselbergs, Folkert W" uniqKey="Asselbergs F" first="Folkert W." last="Asselbergs">Folkert W. Asselbergs</name><name sortKey="Asselbergs, Folkert W" sort="Asselbergs, Folkert W" uniqKey="Asselbergs F" first="Folkert W." last="Asselbergs">Folkert W. Asselbergs</name><name sortKey="Bieringa, Rob J" sort="Bieringa, Rob J" uniqKey="Bieringa R" first="Rob J." last="Bieringa">Rob J. Bieringa</name><name sortKey="Boomsma, Dorret" sort="Boomsma, Dorret" uniqKey="Boomsma D" first="Dorret" last="Boomsma">Dorret Boomsma</name><name sortKey="Boomsma, Dorret" sort="Boomsma, Dorret" uniqKey="Boomsma D" first="Dorret" last="Boomsma">Dorret Boomsma</name><name sortKey="Brundel, Bianca J J M" sort="Brundel, Bianca J J M" uniqKey="Brundel B" first="Bianca J. J. M." last="Brundel">Bianca J. J. M. Brundel</name><name sortKey="De Bakker, Paul I W" sort="De Bakker, Paul I W" uniqKey="De Bakker P" first="Paul I. W." last="De Bakker">Paul I. W. De Bakker</name><name sortKey="De Bakker, Paul I W" sort="De Bakker, Paul I W" uniqKey="De Bakker P" first="Paul I. W." last="De Bakker">Paul I. W. De Bakker</name><name sortKey="De Geus, Eco J C" sort="De Geus, Eco J C" uniqKey="De Geus E" first="Eco J. C." last="De Geus">Eco J. C. De Geus</name><name sortKey="De Geus, Eco J C" sort="De Geus, Eco J C" uniqKey="De Geus E" first="Eco J. C." last="De Geus">Eco J. C. De Geus</name><name sortKey="Dierckx, Bram" sort="Dierckx, Bram" uniqKey="Dierckx B" first="Bram" last="Dierckx">Bram Dierckx</name><name sortKey="Dierckx, Bram" sort="Dierckx, Bram" uniqKey="Dierckx B" first="Bram" last="Dierckx">Bram Dierckx</name><name sortKey="Dietrich, Andrea" sort="Dietrich, Andrea" uniqKey="Dietrich A" first="Andrea" last="Dietrich">Andrea Dietrich</name><name sortKey="Felix, Janine F" sort="Felix, Janine F" uniqKey="Felix J" first="Janine F." last="Felix">Janine F. Felix</name><name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H." last="Franco">Oscar H. Franco</name><name sortKey="Gademan, Maaike G J" sort="Gademan, Maaike G J" uniqKey="Gademan M" first="Maaike G. J." last="Gademan">Maaike G. J. Gademan</name><name sortKey="Hartman, Catharina A" sort="Hartman, Catharina A" uniqKey="Hartman C" first="Catharina A." last="Hartman">Catharina A. Hartman</name><name sortKey="Hemerich, Daiane" sort="Hemerich, Daiane" uniqKey="Hemerich D" first="Daiane" last="Hemerich">Daiane Hemerich</name><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><name sortKey="Jansen, Rick" sort="Jansen, Rick" uniqKey="Jansen R" first="Rick" last="Jansen">Rick Jansen</name><name sortKey="Kors, Jan A" sort="Kors, Jan A" uniqKey="Kors J" first="Jan A." last="Kors">Jan A. Kors</name><name sortKey="Krijthe, Bouwe P" sort="Krijthe, Bouwe P" uniqKey="Krijthe B" first="Bouwe P." last="Krijthe">Bouwe P. 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Loretto Munoz</name><name sortKey="Navis, Gerjan" sort="Navis, Gerjan" uniqKey="Navis G" first="Gerjan" last="Navis">Gerjan Navis</name><name sortKey="Neijts, Melanie" sort="Neijts, Melanie" uniqKey="Neijts M" first="Melanie" last="Neijts">Melanie Neijts</name><name sortKey="Neijts, Melanie" sort="Neijts, Melanie" uniqKey="Neijts M" first="Melanie" last="Neijts">Melanie Neijts</name><name sortKey="Nivard, Michel" sort="Nivard, Michel" uniqKey="Nivard M" first="Michel" last="Nivard">Michel Nivard</name><name sortKey="Nivard, Michel" sort="Nivard, Michel" uniqKey="Nivard M" first="Michel" last="Nivard">Michel Nivard</name><name sortKey="Oldehinkel, Albertine J" sort="Oldehinkel, Albertine J" uniqKey="Oldehinkel A" first="Albertine J." last="Oldehinkel">Albertine J. 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Zafarmand</name><name sortKey="Zafarmand, Mohammad H" sort="Zafarmand, Mohammad H" uniqKey="Zafarmand M" first="Mohammad H." last="Zafarmand">Mohammad H. Zafarmand</name></country><country name="Australie"><noRegion><name sortKey="Amare, Azmeraw T" sort="Amare, Azmeraw T" uniqKey="Amare A" first="Azmeraw T." last="Amare">Azmeraw T. Amare</name></noRegion></country><country name="Éthiopie"><noRegion><name sortKey="Amare, Azmeraw T" sort="Amare, Azmeraw T" uniqKey="Amare A" first="Azmeraw T." last="Amare">Azmeraw T. 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Sinner</name><name sortKey="Sinner, Moritz F" sort="Sinner, Moritz F" uniqKey="Sinner M" first="Moritz F." last="Sinner">Moritz F. Sinner</name><name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name><name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><name sortKey="Voss, Andreas" sort="Voss, Andreas" uniqKey="Voss A" first="Andreas" last="Voss">Andreas Voss</name><name sortKey="Waldenberger, Melanie" sort="Waldenberger, Melanie" uniqKey="Waldenberger M" first="Melanie" last="Waldenberger">Melanie Waldenberger</name><name sortKey="Waldenberger, Melanie" sort="Waldenberger, Melanie" uniqKey="Waldenberger M" first="Melanie" last="Waldenberger">Melanie Waldenberger</name></country><country name="Italie"><noRegion><name sortKey="Salvi, Erika" sort="Salvi, Erika" uniqKey="Salvi E" first="Erika" last="Salvi">Erika Salvi</name></noRegion><name sortKey="Barcella, Matteo" sort="Barcella, Matteo" uniqKey="Barcella M" first="Matteo" last="Barcella">Matteo Barcella</name><name sortKey="Cusi, Daniele" sort="Cusi, Daniele" uniqKey="Cusi D" first="Daniele" last="Cusi">Daniele Cusi</name><name sortKey="Cusi, Daniele" sort="Cusi, Daniele" uniqKey="Cusi D" first="Daniele" last="Cusi">Daniele Cusi</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Wong, Andrew" sort="Wong, Andrew" uniqKey="Wong A" first="Andrew" last="Wong">Andrew Wong</name></noRegion><name sortKey="Asselbergs, Folkert W" sort="Asselbergs, Folkert W" uniqKey="Asselbergs F" first="Folkert W." last="Asselbergs">Folkert W. Asselbergs</name><name sortKey="Britton, Annie R" sort="Britton, Annie R" uniqKey="Britton A" first="Annie R." last="Britton">Annie R. Britton</name><name sortKey="J Rvelin, Marjo Riitta" sort="J Rvelin, Marjo Riitta" uniqKey="J Rvelin M" first="Marjo-Riitta" last="J Rvelin">Marjo-Riitta J Rvelin</name><name sortKey="Kivimaki, Mika" sort="Kivimaki, Mika" uniqKey="Kivimaki M" first="Mika" last="Kivimaki">Mika Kivimaki</name><name sortKey="Kuh, Diana" sort="Kuh, Diana" uniqKey="Kuh D" first="Diana" last="Kuh">Diana Kuh</name><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name><name sortKey="Kumari, Meena" sort="Kumari, Meena" uniqKey="Kumari M" first="Meena" last="Kumari">Meena Kumari</name><name sortKey="Lindgren, Cecilia M" sort="Lindgren, Cecilia M" uniqKey="Lindgren C" first="Cecilia M." last="Lindgren">Cecilia M. Lindgren</name><name sortKey="Lindgren, Cecilia M" sort="Lindgren, Cecilia M" uniqKey="Lindgren C" first="Cecilia M." last="Lindgren">Cecilia M. Lindgren</name><name sortKey="Mahajan, Anubha" sort="Mahajan, Anubha" uniqKey="Mahajan A" first="Anubha" last="Mahajan">Anubha Mahajan</name><name sortKey="Morris, Andrew P" sort="Morris, Andrew P" uniqKey="Morris A" first="Andrew P." last="Morris">Andrew P. Morris</name><name sortKey="Morris, Andrew P" sort="Morris, Andrew P" uniqKey="Morris A" first="Andrew P." last="Morris">Andrew P. Morris</name><name sortKey="Zabaneh, Delilah" sort="Zabaneh, Delilah" uniqKey="Zabaneh D" first="Delilah" last="Zabaneh">Delilah Zabaneh</name><name sortKey="Zabaneh, Delilah" sort="Zabaneh, Delilah" uniqKey="Zabaneh D" first="Delilah" last="Zabaneh">Delilah Zabaneh</name></country><country name="Émirats arabes unis"><noRegion><name sortKey="Bayoumi, Riad" sort="Bayoumi, Riad" uniqKey="Bayoumi R" first="Riad" last="Bayoumi">Riad Bayoumi</name></noRegion></country><country name="Norvège"><noRegion><name sortKey="Christophersen, Ingrid" sort="Christophersen, Ingrid" uniqKey="Christophersen I" first="Ingrid" last="Christophersen">Ingrid Christophersen</name></noRegion></country><country name="Suisse"><noRegion><name sortKey="Ehret, George B" sort="Ehret, George B" uniqKey="Ehret G" first="George B." last="Ehret">George B. Ehret</name></noRegion><name sortKey="Zu Schwabedissen, Henriette Meyer" sort="Zu Schwabedissen, Henriette Meyer" uniqKey="Zu Schwabedissen H" first="Henriette Meyer" last="Zu Schwabedissen">Henriette Meyer Zu Schwabedissen</name></country><country name="Brésil"><noRegion><name sortKey="Hemerich, Daiane" sort="Hemerich, Daiane" uniqKey="Hemerich D" first="Daiane" last="Hemerich">Daiane Hemerich</name></noRegion></country><country name="France"><noRegion><name sortKey="Jouven, Xavier" sort="Jouven, Xavier" uniqKey="Jouven X" first="Xavier" last="Jouven">Xavier Jouven</name></noRegion></country><country name="Belgique"><noRegion><name sortKey="Kuznetsova, Tatiana" sort="Kuznetsova, Tatiana" uniqKey="Kuznetsova T" first="Tatiana" last="Kuznetsova">Tatiana Kuznetsova</name></noRegion><name sortKey="Staessen, Jan A" sort="Staessen, Jan A" uniqKey="Staessen J" first="Jan A." last="Staessen">Jan A. Staessen</name></country><country name="Pologne"><noRegion><name sortKey="Stolarz Skrzypek, Katarzyna" sort="Stolarz Skrzypek, Katarzyna" uniqKey="Stolarz Skrzypek K" first="Katarzyna" last="Stolarz-Skrzypek">Katarzyna Stolarz-Skrzypek</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= Genetic loci associated with heart rate variability and their effects on cardiac disease risk
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